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Acta Pharm Hung ; 73(2): 92-6, 2003.
Article in Hungarian | MEDLINE | ID: mdl-14702689

ABSTRACT

Free radical elimination properties of anticarcinogenic CoD tea were studied in vitro in our laboratory. Therefore its antioxidant effect, lipid-hydroperoxide elimination property and reductive capacity were measured. The isoenzyme composition of CoD tea lipoxygenases was deduced from pH dependence of its lipoxygenase activity. It was found that the antioxidant effect and lipid-hydroperoxide elimination property of CoD tea were comparable with those of ascorbic acid and the reductive capacity of a cup of CoD tea and 11-13 mg ascorbic acid were the same. In spite of the heat sensibility of lipoxygenases, a strong lipoxygenase activity (1102 U/g) of CoD tea was detected in acidic medium (pH 4.5). It is supposed that these free radical elimination properties support anticarcinogenic effect of CoD tea.


Subject(s)
Antioxidants/pharmacology , Lipoxygenase/metabolism , Tea/chemistry , Free Radicals/metabolism , Hydrogen-Ion Concentration , Tea/enzymology
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