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1.
Cureus ; 15(8): e42836, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37664273

ABSTRACT

INTRODUCTION:  Obstructive sleep apnea (OSA), caused by airway narrowing, is likely to occur if the mandibular plane to hyoid distance is greater than 15.4 mm and the posterior airway space (PAS) is less than 11 mm. OSA may be caused by mandibular deficit, bimaxillary retrusion, increased lower facial height, extended soft palate, a large tongue base, and a posteroinferiorly positioned hyoid bone. Snoring and drowsiness during exercise are symptoms of OSA, which is a risk factor for high blood pressure, heart disease, and stroke, and these can result in car crashes. However, orthognathic surgery can improve dental occlusion and aesthetics by adjusting facial bone position, shape, and size. When bones move, the position and tension of soft tissues change. These novel soft tissue interactions, especially when anteroposterior, change the face's appearance and PAS dimensions. This study uses barium sulfate paste to enhance lateral cephalograms before and after orthognathic surgery to assess posterior pharyngeal airway changes. MATERIALS AND METHODS:  Barium sulfate was mixed with water to make a paste for the tongue's dorsum. A preoperative digital lateral cephalogram was obtained, and a postoperative evaluation was conducted six weeks after the procedure. In the cephalostat, the Frankfort horizontal and median planes were aligned parallel to the floor, and a radiograph was taken after the breathing cycle to standardize the hyoid bone location. Preoperative lateral cephalogram analysis using Burstone's hard tissue landmarks confirmed skeletal class II or III deformities. First, the narrowest part of the posterior pharyngeal airway was measured. Second, the narrowest portion between the soft palate and posterior pharyngeal wall parallel to the Frankfort horizontal plane was measured preoperatively, and the procedure was repeated six weeks postop. RESULTS:  Complexity characterizes the pharyngeal airway, which, along with the surrounding structures, facilitates the bodily functions of eating, talking, and breathing. The pharyngeal airway is located behind the nose, mouth, and larynx, and adjusting the jaws changes the size and structure of the pharyngeal airway and surrounding soft tissues, which may affect breathing. A statistically significant change is detected in the posterior palatal and posterior lingual airways after different orthognathic operations. After the mandible is moved forward, both the posterior palatal and posterior lingual airways enlarge. Furthermore, the soft palate exhibits slight decreases in length, thickness, and angle. Additionally, there is an anterosuperior displacement of the hyoid bone. Following maxillary superior impaction, mandibular autorotation is seen in a counterclockwise direction, which has the same result as that of mandibular advancement. CONCLUSION:  It is essential to consider these soft tissue changes when planning orthognathic procedures, as alterations in the pharyngeal airway may impact the patient's postoperative breathing and overall health. Patients with OSA or those at risk of developing it should be closely evaluated and managed appropriately during the surgical planning process.

2.
Semin Thorac Cardiovasc Surg ; 27(3): 331-8, 2015.
Article in English | MEDLINE | ID: mdl-26708380

ABSTRACT

We studied the effect of preoperative determinants on early outcomes of 1028 consecutive infant heart operations in a limited-resource setting. Comprehensive data on pediatric heart surgery (January 2010-December 2012) were collected prospectively. Outcome measures included in-hospital mortality, prolonged ventilation (>48 hours), and bloodstream infection (BSI) after surgery. Preoperative variables that showed significant individual association with outcome measures were entered into a logistic regression model. Weight at birth was low in 224 infants (21.8%), and failure to thrive was common (mean-weight Z score at surgery was 2.72 ± 1.7). Preoperatively, 525 infants (51%) needed intensive care, 69 infants (6.7%) were ventilated, and 80 infants (7.8%) had BSI. In-hospital mortality (4.1%) was significantly associated with risk adjustment for congenital heart surgery-1 (RACHS-1) risk category (P < 0.001). Neonatal status, preoperative BSI, and requirement of preoperative intensive care and ventilation had significant individual association with adverse outcomes, whereas low birth weight, prematurity, and severe failure to thrive (weight Z score <-3) were not associated with adverse outcomes. On multivariable logistic regression analysis, preoperative sepsis (odds ratio = 2.86; 95% CI: 1.32-6.21; P = 0.008) was associated with mortality. Preoperative intensive care unit stay, ventilation, BSI, and RACHS-1 category were associated with prolonged postoperative ventilation and postoperative sepsis. Neonatal age group was additionally associated with postoperative sepsis. Although severe failure to thrive was common, it did not adversely affect outcomes. In conclusions, preoperative BSI, preoperative intensive care, and mechanical ventilation are strongly associated with adverse outcomes after infant cardiac surgery in this large single-center experience from a developing country. Failure to thrive and low birth weight do not appear to adversely affect surgical outcomes.


Subject(s)
Cardiac Surgical Procedures/methods , Health Resources/statistics & numerical data , Heart Defects, Congenital/surgery , Risk Assessment , Cardiac Surgical Procedures/mortality , Female , Heart Defects, Congenital/mortality , Hospital Mortality/trends , Humans , India/epidemiology , Infant , Infant, Newborn , Male , Risk Factors , Survival Rate/trends , Time Factors , Treatment Outcome
3.
J Clin Diagn Res ; 8(9): ZC07-10, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25386511

ABSTRACT

OBJECTIVE: To determine the relationship between the changes of soft and hard tissues after anterior segmental osteotomy and to evaluate these changes using cepahalometric and photometric analyses. MATERIALS AND METHODS: Ten patients aged 18-30 years who underwent anterior segmental osteotomy were included in the study. Preoperative and postoperative records consisted of lateral cephalogram and frontal and lateral photographs. Postoperative measurements were taken six months after surgery. RESULTS: Statistical analysis showed changes in both soft and hard tissue parameters. Changes were not uniform for all the parameters. Upper lip and upper incisor protrusion showed very large effect size whereas nasal tip inclination showed small effect and mentolabial angle showed no effect. CONCLUSION: Skeletal protrusion pose problem to orthodontists as they can't be corrected by orthodontics alone. Anterior segmental osteotomy in association with orthodontia is the choice of treatment. Anterior segmental osteotomy allows for functional and aesthetical correction with good success rate and minimal complication.

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