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1.
Eksp Klin Farmakol ; 72(5): 46-9, 2009.
Article in Russian | MEDLINE | ID: mdl-19928577

ABSTRACT

Chronic experiments on stray dogs with modeling peritonitis showed that a complex therapy involving etoxidol favors improvement of the electrophysiological and metabolic heart activity and provides correction of the lipid distress syndrome. It is established that the lipid regulating effect of etoxidol is related not only to a decrease in the intensity of lipid peroxidation (LPO), but also to the A2-phospholipasae activity of this drug.


Subject(s)
Cardiotonic Agents/pharmacology , Endotoxemia/drug therapy , Lipid Peroxidation/drug effects , Myocardium/metabolism , Phospholipases A2/metabolism , Pyridines/pharmacology , Animals , Disease Models, Animal , Dogs , Endotoxemia/etiology , Endotoxemia/metabolism , Female , Male , Peritonitis/drug therapy , Peritonitis/etiology , Peritonitis/metabolism
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