The effect of leukocyte- and platelet-rich fibrin on the bone loss and primary stability of implants placed in posterior maxilla: a randomized clinical trial.

PURPOSE: In this study, we investigated the effects of leukocyte- and platelet-rich fibrin (L-PRF) on implant stability and alterations in the marginal bone surrounding posterior maxillary implants. METHODS: This randomized clinical trial was conducted to compare the variable of L-PRF placement around maxillary implants. Resonance frequency analysis (RFA) was used to evaluate the implant stability immediately after surgery and at 1, 2, 4, 6, 8, and 12 weeks after surgery (t0 to t6, respectively). In addition, the amount of marginal bone changes around the implant at t6 was compared with the baseline using periapical radiography. RESULTS: The RFA outcomes were statistically significant within each group (P < 0.001, Eta2 = 0.322); however, in none of the follow-ups and immediately after the surgery, there was a significant difference between the two groups in terms of the implant stability quotient (ISQ) scores (P > 0.05). At t0, the test and control groups' respective mean levels of marginal bone loss around the implants were 0.4836 mm and 0.7343 mm, significantly different from the corresponding values at t6. On the other hand, marginal bone loss around the implant was not significantly different between the two groups in t0 and t6 (P = 0.532). CONCLUSIONS: L-PRF did not improve the RFA outcomes of implants three months after implant placement, and changes in the ISQ values over time were the same in both groups. In addition, L-PRF had no superior effect on the marginal bone loss around the implants. TRIAL REGISTRATION NUMBER: The research was registered in the Iranian Registry of Clinical Trials on 22 December 2020 (No: IRCT20200624047906N1), available at http://www.irct.ir.

Assessing the Surface Modifications of Contaminated Sandblasted and Acid-Etched Implants Through Diode Lasers of Different Wavelengths: An In Vitro Study.

Objective: The present study was conducted to compare the effects of 810 nm, 980 nm, and dual (810: 50%-980: 50%) diode lasers on the surface modifications of implants contaminated by a standard strain of Escherichia coli. Methods: Based on the operation on their surface, the implants were divided into six groups: "Group 1" was the positive control group undergoing no specific procedures. "Groups 2, 3, 4, 5, and 6" were contaminated by a standard strain of E. coli; "Group 2" was also set as the negative control group. "Groups 3, 4, and 5" were irradiated by 810 nm, 980 nm, and dual lasers (810: 50%-980: 50%; 1.5W, 320 µm fiber) for 30 sec, respectively. "Group 6" was treated using standard titanium brushes. All groups were examined to evaluate the surface modifications by the X-ray diffraction analysis, scanning electron microscope, and atomic force microscopy. Results: The values of carbon, oxygen, aluminum, titanium, and vanadium were significantly different in the surface composition of the contaminated implants from the control groups (p = 0.010, 0.033, 0.044, 0.016, and 0.037, respectively). In all target areas, there were significant differences in surface roughness (p < 0.0001); the same was also true about the pairwise comparison of the study groups (p < 0.0001). "Group 5" demonstrated lower morphological surface changes and roughness degrees. Conclusions: Overall, laser irradiation could alter the surfaces of the contaminated implants. Titanium brushes and 810/980 nm lasers resulted in similar morphological alterations. Dual lasers enjoyed the least degree of morphological alterations and surface roughness.

Oral rehabilitation with dental implants in patients with systemic sclerosis: A systematic review.

OBJECTIVE: To assess the influence of systemic sclerosis (SSc) on the survival rate of dental implants in SSc patients receiving implant-supported treatments. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) Statement and the Cochrane Collaboration's guiding principles were followed during the study's execution. The data from three databases, PubMed, Google Scholar, and Scopus, available until January 2023, were used to compile the material for our research. Only English-language publications were submitted for this research and evaluated based on their titles, abstracts, and full texts. For performing a quality assessment, quality scores were calculated. RESULTS: The total number of patients and implants studied were 37 and 153, respectively, all having had scleroderma. The patients' ages ranged from 28 to 77 years old, with a mean (SD) age of 58.16 (12.88). All the patients in the case reports and most in the case series study were female. The range of follow-up duration was from 1 to 10 years. In case report studies, the survival rate was 100%; in case series, it was 89.2%. CONCLUSION: The SSc status had no discernible impact on the implant survival rate. Implant-based treatments in SSc patients should not worsen the overall morbidity and should not conflict with systemic treatments. Before starting implant therapy, a thorough risk assessment is essential, though.