1.
J Org Chem
; 73(22): 9188-91, 2008 Nov 21.
Article
in English
| MEDLINE
| ID: mdl-18947253
ABSTRACT
An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, alpha-bromoacetate, and alpha-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.