1.
Clin Vaccine Immunol
; 17(1): 176-9, 2010 Jan.
Article
in English
| MEDLINE
| ID: mdl-19923571
ABSTRACT
DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain.