1.
RSC Chem Biol
; 1(2): 56-59, 2020 Jun 01.
Article
in English
| MEDLINE
| ID: mdl-34458748
ABSTRACT
We report combinations of a DMAP-based catalyst and phenyl acetate with optimal electron density as a new chemical system for high-yield, selective synthetic acetylation of histone lysine residues. The utility of this chemical system as a unique biologic tool is demonstrated by applying it to Xenopus laevis sperm chromatin.