ABSTRACT
In August 2009, the American Association of Colleges of Pharmacy (AACP) Council of Sections established a Task Force to assess the current status of compounding education at its member institutions and to provide recommendations for future direction. The Task Force conducted a survey in late June 2010 of faculty members enrolled in the AACP Pharmaceutics and Pharmacy Practice sections to gain qualitative information of the current state of compounding education. The survey results were then organized around eight curricular topics for which the Task Force members provided interpretations and recommendations. A final report was sent to the AACP Council of Sections on February 15, 2011. This publication provides the information contained in that final report to the professional community.
Subject(s)
Drug Compounding/methods , Education, Pharmacy/methods , Schools, Pharmacy/organization & administration , Curriculum , Educational Measurement , Humans , Societies , Surveys and Questionnaires , Time FactorsABSTRACT
Topical preparations represent a large percentage of compounded prescriptions, particularly in the area of dermatology. Properties of ointment bases vary greatly, and active ingredients are frequently added as aqueous or alcoholic solutions. Currently, there are no quantitative guidelines stating the various water and alcohol absorption capacity of different bases. A short experiment was designed to quantitate the amount of water or alcohol that could be absorbed by a series of ointment bases of varying types. Our findings may be used to assist compounding pharmacists in deciding what base is most suitable to use when considering the amount of water, alcohol, or any similar solvent needed to compound the preparation. A general overview of issues related to topical medication compounding is also provided in this article.
ABSTRACT
Pharmaceutical excipients may have a great effect on properties affecting tablet production. To determine if formulations containing theophylline anhydrous would have properties allowing them to be easily tableted, functional parameters affecting powder flow were evaluated. The Carr Flowability Indices were used for this evaluation. Formulations to be studied include theophylline anhydrous as the active ingredient, hydrous lactose and dicalcium phosphate dihydrate as diluents, polyvinylpyrrolidone as a binder, and fumed silica as a flow promoter. The effect of each component on powder flow is discussed.
