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Adv Gerontol ; 21(1): 127-31, 2008.
Article in Russian | MEDLINE | ID: mdl-18546837

ABSTRACT

The condition of mucociliary system has been studied in 246 patients with chronic obstructive pulmonary diseases. It is stated that chronic obstructive pulmonary diseases patients observe the significant variation of bronchial clearance's tempos, imbalance in the system of lipids' peroxide oxidation and antioxidant defense during aggravation and remission. Dysfunction of mucociliary transport is associated with the changes of mucilaginous elastic characteristics of tracheal-bronchial secretion that leads to progression of bronchial obstruction.


Subject(s)
Aging/physiology , Lipid Peroxidation , Mucociliary Clearance/physiology , Mucus/metabolism , Pulmonary Disease, Chronic Obstructive/physiopathology , Aged , Aging/metabolism , Antioxidants/metabolism , Female , Humans , Male , Middle Aged , Mucus/chemistry , Pulmonary Disease, Chronic Obstructive/metabolism , Severity of Illness Index , Time Factors
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