A Comparative Study to Assess the Add on Effects of Probiotic in Allergic Rhinitis Patients in a Tertiary Care Hospital.

Probiotic intervention may have a promising role in the prevention of AR, in preventing allergic diseases including AR. Probiotics can exert beneficial effects on the host through distinct cellular and molecular pathways, these mechanisms of action may vary from one kind of probiotic to another for the same immune response and may be regulated by a combination of several events. Material and methods- Research site-Tertiary Care Government Hospital and Medical College in a major metropolitan city.TYPE OF STUDY-Prospective comparative Study.No. of Subjects -100 cases.Study Duration-Duration for collection of data-24 months.Sample size -100 patientsData Collection:Was collected from data of case proforma of all patients.Mode of Selection -Patients presenting in Out Patient Department (OPD)and In PatientDepartment(IPD) who meet the inclusion criteria and who consent to be a part of the study.Results-Significant difference was found in 12 weeks of treatment among group A and group B. Mild symptoms were seen more after 12 weeks in group B while severity of symptom reduction was less in group A as compared to group B in 12 weeks of treatment.Conclusion Probiotic intervention may have a promising role in the prevention of AR, in preventing allergic diseases including AR.Probiotics can exert beneficial effects on the host through distinct cellular and molecular pathways, these mechanisms of action may vary from one kind of probiotic to another for the same immune response and may be regulated by a combination of several events. Thus making probiotics' mechanism of action a challenging, complex, and fertile area for investigation. Probiotics appear to prevent allergy recurrences, alleviate the severity of symptoms and improve the quality of life of patients with allergic rhinitis.

An Effective Method to Collect Bone Dust for Mastoid Cavity Obliteration.

To compare the volume of cortical bone dust collected and the time taken for bone dust collection by using a self-devised bone dust collector and that by manual method using a metal scoop in patients undergoing modified radical mastoidectomy with mastoid cavity obliteration. A prospective study was done in 62 patients of cholesteatoma. They underwent canal wall down mastoidectomy. Mastoid cavity was obliteration was done using cortical bone dust collected after dividing the patients randomly into 2 groups: (1) using a collector device made using a mucous extractor fitted with a nylon mesh of size 1″ × 3″ attached to the suction tube, (2) collected manually by using a metal scoop. The time taken for the collection of bone dust was recorded and the volume of bone dust collected was measured and recorded. We found that the time taken for the collection of bone dust was significantly lower and the volume of bone dust collected was higher using a mucous extractor as compared to that by manual collection using a metal scoop. The suction based mucous extractor performed better in terms of both time taken for collection and also in the volume of cortical bone dust that was collected as compared to manual collection using a metal scoop. Therefore, we conclude from our study that using the suction based mucous extractor is a more effective method of cortical bone dust collection for mastoid cavity obliteration.

Endoscopic assisted removal - An aesthetic approach to impacted third molar tooth in the orbital floor.

A third molar displaced in the orbital floor is a very rare sighting. The usual surgical approach to such a case is the Caldwell Luc procedure that has its own complications. Here in this article, we present a 17-year-old male patient with third molar displaced in the orbital floor with egg shell thin anterior wall. The aim of the article is to report the unusuality of the case and to emphasize the endoscopic assisted approach to the orbital floor through a relatively small sub-labial incision. Endoscope aids in preserving the integrity of vital structures, facial aesthetics and complete eradication of the disease with faster recovery. Though, endoscopic approach requires requisite expertise, it is a learnable skill and can be mastered with ease.

Effects of hypertension on hearing.

To determine the likely association between hypertension and hearing loss. 150 cases and 124 controls, both genders, aged 45-64, included in the research after sample estimation. Hypertension was verified through blood pressure readings and was classified as grade 1, grade 2 and grade 3 hypertension or no hypertension according to the blood pressure readings. Hearing was assessed by measuring pure tone threshold at various frequencies ranging between 250 and 8,000 Hz. There is a significant association between hypertension and increase in the hearing threshold. Hearing loss in the population under study suggests that hypertension is an accelerating factor of degeneration of the hearing apparatus due to aging. Association between Increased hearing threshold and hypertension in this research, can allow for an integrated work of cardiologists, nephrologists, otorhinolaryngologists, audiologists and other health professionals concerned with alterations caused by hypertension.

Spirometry as an objective tool for nasal patency.

Spirometry can be used as an objective tool for measuring nasal patency. it is sensitive, easy to perform, comfortable to patient The only limitation being that it only can be done in institution.

Hemangiopericytoma like tumor - a diagnostic challenge.

Haemangjopericytoma is a vascular tumour rarely seen in common practice, especially in head & neck. Hemangjopericytoma - like tumor is an even more rare entity and only 70 cases have been described arising from the nose & paranasal sinuses. The aim of this paper is to review the literature and highlight the ability of the tumor to masquerade as a less ominous, more commonly occurring benign growth of the region thereby making the diagnosis even more elusive.