[Semax in the treatment of glaucomatous optic neuropathy in patients with normalized ophthalmic tone]. / "Semaks" v lechenii glaukomatoznoi opticheskoi neiropatii u bol'nykh s normalizovannym oftal'motonusom.

A complex of neuroprotective therapy, including a new Russian neuropeptide semax, was used in the treatment of glaucoma patients with normalized ophthalmic tone. Electrophysiological and computer methods of examination demonstrated the advantages of new therapy over traditional neuroprotective treatment for glaucoma. The efficiency is due to pathogenetic activity of semax possessing both neuroprotective and neurotrophic effects.

[Nitrogen oxide in the pathogenesis of glaucoma and cataract]. / Oksid azota v patogeneze glaukomy i katarakty.

The content of nitrite (final metabolite of nitroradical) was measured in aqueous humor of patients with glaucoma and cataract. The level of NO formation is increased at the initial stage of glaucoma and decreases with the disease progress. A direct correlation between the level of nitrite in aqueous humor and coefficient of easiness of its discharge was detected. Cataract is associated with a high level of nitrite in intraocular fluid. The results are discussed from the viewpoint of ocular hydro--and hemodynamic regulation and NO involvement in the free radical oxidation reactions, playing an important role in the pathogenesis of both diseases.