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1.
Bull Exp Biol Med ; 147(6): 711-4, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19902064

ABSTRACT

Antiinflammatory effects of water-alcohol extracts and sum of alkaloids from the aerial part of delphinium under conditions of immune inflammation caused by Freund's complete adjuvant were comparable to activity of orthophen, a classical antiinflammatory drug. Normalizing effects of the studied extracts on hematological and biochemical parameters were demonstrated.


Subject(s)
Alkaloids/therapeutic use , Anti-Inflammatory Agents/therapeutic use , Arthritis, Experimental/drug therapy , Delphinium/chemistry , Freund's Adjuvant/pharmacology , Plant Extracts/therapeutic use , Alkaloids/chemistry , Animals , Anti-Inflammatory Agents/chemistry , Arthritis, Experimental/chemically induced , Arthritis, Experimental/pathology , Edema/chemically induced , Edema/drug therapy , Extremities , Hyperemia/chemically induced , Hyperemia/drug therapy , Male , Plant Extracts/chemistry , Rats
2.
Bull Exp Biol Med ; 145(6): 724-7, 2008 Jun.
Article in English | MEDLINE | ID: mdl-19110561

ABSTRACT

Effects of complex and individual bioactive substances extracted from tall delphinium on acute inflammation induced by carrageenin, acetic acid, serotonin, and histamine were studied. The studied plant substances produced a pronounced antiinflammatory effect comparable to that of nonsteroid antiinflammatory drugs.


Subject(s)
Anti-Inflammatory Agents/pharmacology , Delphinium/chemistry , Inflammation/drug therapy , Plant Extracts/pharmacology , Acetic Acid , Acute Disease , Animals , Anti-Inflammatory Agents/therapeutic use , Carrageenan , Histamine , Inflammation/chemically induced , Mice , Phytotherapy/methods , Plant Extracts/therapeutic use , Serotonin
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