ABSTRACT
Annually about 6,5 thousands of military servicemen retire due to cardiovascular diseases, every second serviceman retires before superannuation. Stress echocardiography in comparison with other imaging studies is cheaper, safer and matches in sensibility and specificity. The prevalence of stress echocardiography and stress systems can make it available in district, central and main hospitals, and clinics of the Kirov Military Medical Academy. It is proposed to expand indications for stress echocardiography for certain contingent soldiers: those senior commanders, aircrew, and divers soldiers at high risk of cardiovascular complications. For training of specialists in the filed of stress echocardiography in the Kirov Military Medical Academy themed cycles for medical ultrasound and functional diagnostics are orginised.
Subject(s)
Cardiovascular Diseases/diagnostic imaging , Echocardiography, Stress/methods , Hospitals, Military , Military Medicine/methods , Military Personnel , Adult , Cardiovascular Diseases/epidemiology , Female , Humans , MaleABSTRACT
Effectiveness and informativity of various experimental pharmacological models of the chronic heart failure (CCF) in rats have been evaluated by means of ultrasonic cardiography. It has been established that isoproterenol (INN isoprenaline) (80 mg/kg, s.c., twice with an interval of 24 h) produces compensated CCF. Monocrotaline (single dose 60 mg/kg, i.p.) caused the development of pulmonary hypertension, right ventricle hypertrophy, and pronounced right ventricle failure in a fraction of experimental rats. Doxorubicin administration (cumulative doze 15 mg/kg, i.p., divided into 6 injections within 14 days) resulted in decreased left ventricle contractility, eccentric heart remodeling, and CCF development in most cases. Thus, the doxorubicin-induced disorder in rats can be considered the most effective pharmacological model of CCF, leading to the development of pronounced and progressive CCF in the majority of experimental animals.
