Insight into the Spin Properties in Undoped and Mn-Doped CdSe/CdS-Seeded Nanorods by Optically Detected Magnetic Resonance.

Controlling the spin degrees of freedom of photogenerated species in semiconductor nanostructures via magnetic doping is an emerging scientific field that may play an important role in the development of new spin-based technologies. The current work explores spin properties in colloidal CdSe/CdS:Mn seeded-nanorod structures doped with a dilute concentration of Mn2+ ions across the rods. The spin properties were determined using continuous-wave optically detected magnetic resonance (ODMR) spectroscopy recorded under variable microwave chopping frequencies. These experiments enabled the deconvolution of a few different radiative recombination processes: band-to-band, trap-to-band, and trap-to-trap emission. The results uncovered the major role of carrier trapping on the spin properties of elongated structures. The magnetic parameters, determined through spin-Hamiltonian simulation of the steady-state ODMR spectra, reflect anisotropy associated with carrier trapping at the seed/rod interface. These observations unveiled changes in the carriers' g-factors and spin-exchange coupling constants as well as extension of radiative and spin-lattice relaxation times due to magnetic coupling between interface carriers and neighboring Mn2+ ions. Overall, this work highlights that the spin degrees of freedom in seeded nanorods are governed by interfacial trapping and can be further manipulated by magnetic doping. These results provide insights into anisotropic nanostructure spin properties relevant to future spin-based technologies.

Sonochemical One-Step Synthesis of Polymer-Capped Metal Oxide Nanocolloids: Antibacterial Activity and Cytotoxicity.

Most antibacterial agents demand their action in the form of a liquid for compatibility and ease of use in biosystems, which are mainly composed of biological fluids. Controlling the colloidal stability of metal oxide nanocolloids, in parallel with minimizing the effect of using a large amount of surfactant on their biocidal activity and cytotoxicity, remains a challenge. Here, we address the stability of nanocolloids of ZnO and CuO in the presence of polymer surfactants and the influence of the surface capping on their antibacterial activity and cytotoxicity. The metal oxide nanoparticles (NPs) were synthesized sonochemically in a single step and tested against both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus to validate their biocidal efficacy. Cytotoxicity studies were performed on human alveolar epithelial cells. Polyethylene glycol- and polyvinyl alcohol-capped NPs are observed to show the minimum cytotoxicity whereas polyethylene imine-capped and pristine metal oxide NPs are toxic to the mammalian cells. The cytotoxic and antibacterial properties of the stable nanocolloids displayed an inverse relation, highlighting the role and significance of the polymer capping. The nontoxic biocidal nanocolloids showed an effective antibacterial efficacy of 99.9% in 2 h.

Graphene-Based "Hot Plate" for the Capture and Destruction of the Herpes Simplex Virus Type 1.

The study of graphene-based antivirals is still at a nascent stage and the photothermal antiviral properties of graphene have yet to be studied. Here, we design and synthesize sulfonated magnetic nanoparticles functionalized with reduced graphene oxide (SMRGO) to capture and photothermally destroy herpes simplex virus type 1 (HSV-1). Graphene sheets were uniformly anchored with spherical magnetic nanoparticles (MNPs) of varying size between ∼5 and 25 nm. Fourier-transform infrared spectroscopy (FT-IR) confirmed the sulfonation and anchoring of MNPs on the graphene sheets. Upon irradiation of the composite with near-infrared light (NIR, 808 nm, 7 min), SMRGO (100 ppm) demonstrated superior (∼99.99%) photothermal antiviral activity. This was probably due to the capture efficiency, unique sheet-like structure, high surface area, and excellent photothermal properties of graphene. In addition, electrostatic interactions of MNPs with viral particles appear to play a vital role in the inhibition of viral infection. These results suggest that graphene composites may help to combat viral infections including, but not only, HSV-1.

Cu0.89Zn0.11O, A New Peroxidase-Mimicking Nanozyme with High Sensitivity for Glucose and Antioxidant Detection.

Nanomaterial-based enzyme mimetics (nanozymes) is an emerging field of research that promises to produce alternatives to natural enzymes for a variety of applications. The search for the most cost-effective and efficient inorganic nanomaterials, such as metal oxides, cannot be won by pristine CuO. However, unlike CuO, the Zn-doped CuO (Zn-CuO) nanoparticles reported in this paper reveal superior peroxidase-like enzyme activity. This places Zn-CuO in a good position to participate in a range of activities aimed at developing diverse enzyme applications. The peroxidase-like activity was tested and confirmed against various chromogenic substrates in the presence of H2O2 and obeyed the Michaelis-Menten enzymatic pathway. The mechanism of enhanced enzymatic activity was proved by employing terephthalic acid as a fluorescence probe and by electron spin resonance. The nanozyme, when tested for the detection of glucose, showed a substantial enhancement in the detection selectivity. The limit of detection (LOD) was also decreased reaching a limit as low as 0.27 ppm. Such a low LOD has not been reported so far for the metal oxides without any surface modifications. Moreover, the nanozyme (Zn-CuO) was utilized to detect the three antioxidants tannic acid, tartaric acid, and ascorbic acid and the relative strength of their antioxidant capacity was compared.

A one-step sonochemical synthesis of stable ZnO-PVA nanocolloid as a potential biocidal agent.

One of the limitations in the applications and commercialization of metal oxides in diverse fields is their inferior colloidal stability. The ability of metal oxide nanoparticles (MONPs) to remain in the suspended form for long duration is influenced by the particle size and the capping efficiency of the surfactant employed. Among the metal oxides, ZnO is exploited as an effective biocidal agent. For practical applications, the incorporation of ZnO into liquids using a stabilizer is of importance, and therefore synthesizing nanoparticles with high dispersity in solution still remains a challenge. The present work is aimed at synthesizing ZnO nanoparticles (NPs) in colloidal form with great stability, minimal particle size and high antibacterial activity. Herein, we report a single step synthesis of ZnO colloids in aqueous medium by using a biocompatible polymer PVA (poly(vinyl alcohol)) as a stabilizing agent. Both ZnO (without PVA) and ZnO-PVA NPs are prepared using ultrasonic irradiation and their differing particle sizes, stabilities and antibacterial activities are correlated. ESR measurements reveal that ZnO NPs of reduced particle size (∼5 nm) produced increased levels of reactive-oxygen species (ROS). The biocidal effect of the colloidal solution was examined on two bacterial species: Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus. The results revealed an enhancement in the antibacterial activity for the ZnO-PVA nanofluid.