1.
Org Lett
; 3(23): 3733-5, 2001 Nov 15.
Article
in English
| MEDLINE
| ID: mdl-11700125
ABSTRACT
[reaction--see text] Carboxylic acids possessing strongly electron withdrawing substituents in the alpha-position in the presence of DCC acylate sterically hindered and chemically sensitive alcohols. The pattern of reactivity, the deuteration experiments, and the formation of a product derived from a [4 + 2] cycloaddition reaction corroborate the existence of ketene intermediates in the reaction.