ABSTRACT
Taraxer-14-en-3beta-ol ( 1) was shown to be the active ingredient in the leaves of Sterculia foetida L. The alcohol 1, its acetate and ketone showed anti-inflammatory activity against TPA induced mouse ear oedema with inhibition ratios of 60.0, 58.57 and 40.57 at 0.5 mg/ear, respectively. The percentage inhibition of inflammation increased with dose for each compound.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Edema/prevention & control , Oleanolic Acid/analogs & derivatives , Oleanolic Acid/pharmacology , Phytotherapy , Plant Extracts/pharmacology , Sterculia , Animals , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Edema/chemically induced , Male , Mice , Oleanolic Acid/administration & dosage , Oleanolic Acid/therapeutic use , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use , Plant LeavesABSTRACT
An alcoholic extract of Sterculia foetida L. leaves was subjected to pharmacological screening using various animal models. The extract caused reduced exploratory activity in mice. Further it potentiated pentobarbitone sleeping time in normal and chronic pentobarbitone-treated mice. It also potentiated barbital sodium-induced hypnosis, indicating central nervous system depressant activity. The extract also exhibited significant antiinflammatory activity in the acute carrageenan-induced rat paw edema and the chronic granuloma pouch models. However, it was devoid of analgesic activity in the tail flick model.
Subject(s)
Campylobacter Infections/diagnosis , Campylobacter jejuni , Diarrhea, Infantile/microbiology , Diarrhea/microbiology , Acute Disease , Anti-Bacterial Agents/therapeutic use , Campylobacter Infections/drug therapy , Campylobacter jejuni/classification , Campylobacter jejuni/growth & development , Child, Preschool , Diarrhea/drug therapy , Diarrhea, Infantile/drug therapy , Feces/microbiology , Humans , India , InfantABSTRACT
One patient of rheumatoid arthritis was treated according to astromedicine. Wearing of Coral beads had remarkable effect on the disease. The interesting finding are reported in this paper.
ABSTRACT
Cutaneous leiomyomas are rarely encountered at birth. In their usual form they appear as discrete dermal papules or nodules with a pink or brown discoloration of the overlying skin. We examined an infant with an unusual mass attached to the right heel at birth. Histologically, the lesion was a leiomyoma. It apparently represented a bizarre proliferative anomaly of smooth muscle occurring during fetal development.
