Design and modeling of diazinon degradation in hydrous matrix by Ni-doped ZnO nanorods under ultrasonic irradiation: process optimization using RSM (CCD), kinetic study, reaction pathway, mineralization, and toxicity assessment.

In first, the Ni-doped ZnO nanorods used as an appeal sonocatalyst was synthesized through co-precipitation method. Afterwards, the crystalline structure, functional groups, surface morphology, and elemental composition were characterized by a set of analysis. Removal of diazinon ((DZ) as a renowned pesticide) was investigated using sonocatalytic performance of US/Ni-doped ZnO system. In this empirical study, response surface methodology (RSM) based central composite design (CCD) was applied for optimization of operational factors. Under the optimum conditions such as initial pH = 5, initial DZ concentration = 15 mg L-1, sonocatalyst dosage = 1 g L-1, and in the presence of organic compounds (oxalic acid, humic acid, and folic acid) = 3 mg L-1, the sonocatalytic degradation of DZ after 15 min was 82.29%. The F-value (6.64) and P-value (< 0.0001) for DZ degradation in the quadratic model imply the proposed model was significant. A-factor (pH) considers as a prominent factor owing to having the highest F-value. In addition, the sonocatalytic data in this study exhibited valid fitting for the first order kinetic model (R2 > 0.98). After six consecutive cycles, the Ni-doped ZnO nanorods could be recyclable for sonocatalytic degradation of DZ. The five main compounds produced during the US/Ni-doped ZnO embracing 2-isopropyl-6-methyl-4-pyrimidinol (IMP), diethyl phosphonate, diazoxon, hydroxyldiazinon, and diazinon methyl ketone are formed in the path of DZ degradation. OFAT style also revealed 99.99% of DZ degradation with 73.26% of mineralization rate in optimum status. The Ni-doped ZnO presented agreeable sonocatalytic facility in the refinement of real water and wastewater matrix. Finally, the results of toxicity evaluation (Daphnia magna) in the sonocatalytic degradation of DZ (by US/Ni-doped ZnO system) showed that the toxicity of the DZ solution lessened under US waves (LC50 and TU 48 h equal to 36.472 and 2.741 volume percent, respectively).

Interactions of Colorectal Cancer, Dietary Fats, and Polymorphisms of Arachidonate Lipoxygenase and Cyclooxygenase Genes: A Literature Review.

Objective: Genetics and dietary factors play important roles in the development of colorectal cancer (CRC). However, the underlying mechanisms of the interactions between CRC, gene polymorphisms, and dietary fat are unclear. This review study investigated the effects of polymorphisms of arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) genes in the association between CRC and dietary fat. Methods: All the related papers published from 2000 to 2022 were collected from different databases such as PubMed, Science Direct, Scopus, and Cochran using related keywords such as colorectal cancer, ALOX, COX, polymorphism, and dietary fat. Non-English and unrelated documents were excluded. Results: Some single-nucleotide polymorphisms (SNPs) in the ALOX and COX genes, such as rs2228065, rs6413416, and rs4986832 in the ALOX gene, and rs689465 in the COX gene may play significant roles in the association between the risk of CRC and dietary fats. SNPs of ALOX and COX genes may influence the effects of dietary fatty acids on the risk of CRC. Conclusion: Some polymorphisms of the ALOX and COX genes may have important roles in the effects of dietary fat on the risk of CRC. If future studies confirm these results, dietary recommendations for preventing colorectal cancer may be personalized based on the genotype of the ALOX and COX genes.

Association of serum 25-OH-vitamin D level with FTO and IRX3 genes expression in obese and overweight boys with different FTO rs9930506 genotypes.

BACKGROUND: The roles of FTO gene and the level of serum 25-OH-vitamin D in obesity are frequently reported. This study aimed to investigate the interactions of serum 25-OH-vitamin D level, FTO and IRX3 genes expression, and FTO genotype in obese and overweight boys. METHODS: This study was carried out on the 120 male adolescents with overweight in Tehran, Iran. Blood samples were collected from the participants in order to evaluate the serum level of 25-OH-vitamin D, the expression level of FTO and IRX3 genes, and FTO genotype for rs9930506 at baseline and after 18 weeks of the study. RESULTS: In general, no significant association was found between serum 25-OH-vitamin D level and IRX3 and FTO genes expression. The results of linear regression on the relationship between 25-OH-vitamin D serum level and FTO and IRX3 genes expression based on FTO genotypes for rs9930506 indicated that in AA/AG genotype carriers, serum 25-OH-vitamin D level was positively associated with FTO gene expression (B = 0.07, p = 0.02) and inversely associated with IRX3 gene expression (B = - 0.07, p = 0.03). In GG carriers, serum 25-OH-vitamin D level was not associated with expression of IRX3 and FTO genes. CONCLUSION: There are significant interactions between 25-OH-vitamin D and the expression of FTO and IRX3 genes in the subset of obese patients with specific genotypes for FTO rs9930506. There was no association between serum 25-OH-vitamin D levels and the expression of FTO and IRX genes in individuals with a homozygous genotype for the risk allele of the FTO gene polymorphism.

Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals.

BACKGROUND AND OBJECTIVE: Exposure to formaldehyde has adverse effects on health both acutely and over the long term (e.g., carcinogenicity). The substance is widely used in pathology and histology departments.  This study focused on cancer risk of formaldehyde in pathology department of five hospitals in Rasht. MATERIALS AND METHODS: Sampling and determination of formaldehyde in pathology department were carried out based on the NIOSH method of 3500. The working condition and working environment were investigated and a semi quantitative risk assessment were used to health risk assessment of formaldehyde and The individual lifetime cancer probability, which is defined as the increase in the probability of developing cancer during continuous exposure to an air pollutant were used to assess health risks with formaldehyde. RESULTS: The results showed that the exposure level of all subjects were higher than the Occupational Exposure Limit for 8 hours exposure time of formaldehyde. However, in the five occupational groups, the highest weekly exposure index was observed for the Lab Technicians (0.664 ppm) at Hospital no. 5, which could have been due to more daily working hours at this sampling site and a lack of adequate ventilation. The formaldehyde concentration was in the 0.0192 to 0.326 ppm ranges for five hospital pathology departments. The cancer risk ranged from 9.52×10-5 to 1.53×10-3, and it was greater than the WHO acceptable cancer risk level. CONCLUSIONS: The results of the risk assessments can be used for managing the chemical exposure of allocated resources for defining control actions. This process plays an important role in reducing the level of exposure to formaldehyde in pathology departments.
.

Application of ZnO nanorods doped with Cu for enhanced sonocatalytic removal of Cr(VI) from aqueous solutions.

The aim of this research was to develop a simple and inexpensive process for reduction of Cr(VI) to Cr(III). Zinc oxide nanoparticles were synthesized with an easy co-precipitation procedure, and the addition of Cu2+ doping agent effectively enhanced the Cr(VI) reduction in the presence of ultrasound (US). XRD, FT-IR, FE-SEM, EDX, VSM, and XPS were used to determine the structural specifications of the zinc oxide nanoparticles. Under optimal conditions such as pH 3, initial Cr(VI) content of 20 mg/L, and catalyst dosage of 0.8 g/L, the ultrasonic/Cu-ZnO process showed a higher sonocatalytic activity (96.83%) than ultrasonic/ZnO (67.36%) after 60 min. By increasing pH and Cr(VI) concentration, the removal efficacy of Cr(VI) declined. The experimental data was well described with the first-order kinetic model. When initial Cr(VI) concentration increased from 10 to 50 mg/L, the first-order rate constant declined from 0.2326 to 0.0019 min-1 and electrical energy per order (EEO) enhanced from 19.81 to 2425.26 kWh/m3. Also, the ultrasonic/Cu-ZnO system exhibited considerable sonocatalytic performance in Cr(VI) reduction in the presence of hydrogen peroxide and citric acid, and complete removal was achieved within 60 min. The presence of anions negatively affected Cr(VI) reduction. Complete reduction was attained when ultrasound was applied at a power of 100 W. The catalyst activity was well maintained up to six consecutive cycles. In addition, the removal efficiency was approximately 62 and 65% for field water and real electroplating wastewater samples, respectively.

Phytoremediation of heavy metals (Ni, Cd, Pb) by Azolla filiculoides from aqueous solution: A dataset.

In this article, the data of heavy metals phytoremediation efficiency were provided. The Azolla was collected from the lake around the Rasht city and washed in tap water, then weighed (0.2, 0.4 and 0.8 g), and kept for 15 days in the 100 ml disposable container in the presence 5, 10 and 25 mg/L of lead, nickel and cadmium ions. The samples were stored in polyethylene containers for analysis of the metal concentration with ICP-OES. According to the results, removal efficiency was increased from 40% to 70% at 10 days along with the increasing of the biomass from 2.0 to 8.0 g. The removal efficiency of Ni (II), Cd (II), and Pb (II) were increased by increasing the contact time up to 10 days. The removal efficiency decreased by increasing of the metals concentration from 5 to 25 mg/L. The highest removal efficiency was observed at heavy metals concentrations of 5 mg/L and contact time of 10 days. Results showed that Azolla had a high potential for the removal of heavy metals from water resources and it can be used in phytoremediation of heavy metals in environmental refinement projects.

Data on corrosive water in the sources and distribution network of drinking water in north of Iran.

This study aimed to determine the parameters of scaling and corrosion potential of drinking water in sources and distribution networks of water supply in two cities of north of Iran. The results of Amlash water sampels analysis in winter revealed that the average values of Langelier, Ryznar, Aggressive, Pockorius, and Larson- skold indices was -1.31, 9.73, 11.5, 9.74 and 0.24, respectively, but, in summer they were -1.51, 10.71, 11.36, 10.72 and 0.25, respectively. For Rudsar, the results of water sampels analysis in winter illustrated that the average values of Langelier, Ryznar, Aggressive, Pockorius, and Larson was -1.12, 9.69, 11.33, 9.19 and 0.16, respectively, while, in summer they were -1.05, 10.04, 11.92, 10.18 and 0.19, respectively. The beneficial of this data is showing the clear image of drinking water quality and can be useful for preventing the economical and safety problems relating to corrosion and scaling of drinking water.

Intrinsic kinetics for fixed bed bioreactor in hospital wastewater treatment.

Variation in hospital wastewater (HWW) pollutants and differences with municipal wastewater (MWW), make the use of biokinetic coefficients obtained from activated sludge in the MWW treatment unprofitable for designing, modeling and evaluation of biological processes for HWW treatment. Since this study was conducted to evaluate the performance and biokinetic coefficients of a fixed bed bioreactor (FBBR) using rice husks as fixed media in HWW treatment, a new modified method was also proposed for biokinetic estimation in FBBR processes. For these purposes, five hydraulic retention times along with five sludge retention times were introduced to a pilot setup and the required data were attained. The performance process for chemical oxygen demand (COD) removal was significant (87.8-97.5%) in different conditions. The values of biokinetic coefficients k, Ks, Y and Kd were obtained as 2.42 (day-1), 55.5 (mgCOD/L), 0.2929 (mgBiomass/mgCOD) and 0.0164 (day-1), respectively. The rice husks with high surface area and high affinity for biomass accumulation on its surface are promising media for a green and environmentally friendly FBBR process. The kinetics parameters values are utilizable for modeling of FBBR using rice husks as fixed media in HWW treatment.