Overset meshing in combination with novel blended weak-strong fluid-structure interactions for simulations of a translating valve in series with a second valve.

Mechanical circulatory support (MCS) devices can bridge the gap to transplant whilst awaiting a viable donor heart. The Realheart Total Artificial Heart is a novel positive-displacement MCS that generates pulsatile flow via bileaflet mechanical valves. This study developed a combined computational fluid dynamics and fluid-structure interaction (FSI) methodology for simulating positive displacement bileaflet valves. Overset meshing discretised the fluid domain, and a blended weak-strong coupling FSI algorithm was combined with variable time-stepping. Four operating conditions of relevant stroke lengths and rates were assessed. The results demonstrated this modelling strategy is stable and efficient for modelling positive-displacement artificial hearts.

Healing Potential of Platelet Rich Fibrin in Impacted Mandibular Third Molar Extraction Sockets.

BACKGROUND: Healing of both hard and soft tissues have become one of the great challenges, faced in clinical research in development of bioactive surgical additives responsible for regulating inflammation and increasing healing. Platelet-rich fibrin (PRF) represents a new step in the platelet gel therapeutic concept with simplified processing minus artificial biochemical modification. AIMS AND OBJECTIVES: The aim of this study is to evaluate the effectiveness of PRF on soft-tissue healing and bone tissue healing in terms of postoperative pain, postoperative swelling, soft tissue healing, and the quality of bone healing at the mandibular third molar socket. MATERIALS AND METHODS: A clinical study will be done on patients reporting to the Department of Oral and Maxillofacial Surgery in Government Dental College, Srinagar, requiring disimpaction of bilateral mesioangular impacted mandibular third molars in 60 patients. RESULTS: The present prospective clinical study evaluates the effect of PRF in healing of mandibular third molar extraction sockets. There was no difference in the age gender and type of impaction between the two groups as the mean postoperative pain score (visual analog scale) was lower for the PRF group (Group A) at all points of time when compared with the control (Group B), and this was statistically significant (P < 0.05). The mean percentage swelling was lower for the PRF group (Group A) at all points of time when compared with the control (Group B). Evaluating the effect of treatments (with or without PRF) on lamina dura score shows that in both the groups at different time periods, significant (P < 0.001) difference was observed on lamina dura score. CONCLUSION: The results of the present study suggest that application of autologous PRF gel has a beneficial effect on the healing of extraction sockets after third molar surgery.

HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells.

The existence of multiple-interactive roles between several signaling pathways in tumorigenesis shows the significance of pharmacological factors like heat shock protein 90 (HSP90) inhibitors which control several signaling pathways simultaneously. HSP90 as a molecular chaperone supports the active conformational structure and function of several oncogenic signal proteins, termed "client" proteins, some of them act as a link between cancer and inflammation. Prostaglandin E2 (PGE2) is one of the major mediators of inflammation in colorectal cancer development and progress. However, the relationship between chaperone activity of HSP90 and PGE2 levels remains unclear. We evaluated the inhibitory effects of 17-demethoxy-17-allylamino geldanamycin (1 7-AAG), an HSP90 inhibitor, on PGE2 levels in HT-29 colorectal cancer cells. For the first time, we showed inhibitory effects of 17-AAG, on PGE2 levels in HT-29 colorectal cancer cells. 17-AAG inhibited PMA-induced cyclooxygenase-2 (COX-2) mRNA expression and protein level. We showed 15-hydroxyprostaglandin dehydrogenase (15-PGDH) expression induced by 17-AAG treatment at both mRNA and protein levels. In conclusion, we found that inhibitory effects of 17-AAG on PGE2 levels in HT-29 colorectal cancer cells were mediated through modulating COX-2 and 15-PGDH expression.

Effect of structure and composition on optical properties of Er-Sc silicates prepared from multi-nanolayer films.

Polycrystalline Er-Sc silicates (Er(x)Sc(2-x)SiO5 and Er(x)Sc(2-x)Si2O7) were fabricated using multilayer nanostructured films of Er2O3/SiO2/Sc2O3 deposited on SiO2/Si substrates by RF- sputtering and thermal annealing at high temperature. RBS, TEM, GIXD, and PL results show the presence of Er(x)Sc(2-x)SiO5 with an emission peak at 1528 nm for annealing from 900 to 1100 °C, and Er(x)Sc(2-x)Si2O7 with an emission peak at 1537 nm for higher annealing temperature. The PL intensity of the Er(x)Sc(2-x)Si2O7 phase is five times stronger than that of the Er(x)Sc(2-x)SiO5 phase at 1250 °C. From PLE and PL spectra of Er(x)Sc(2-x)Si2O7 thin film, we schematically illustrate the Er³âº Stark energy levels of 4I(13/2) to 4I(15/2) manifolds due to the crystal field strength effect of Sc³âº. Temperature-dependent PL of the Er(x)Sc(2-x)Si2O7 phase exhibits a variation of the full-width at half-maximum (FWHM) from 1.1 to 2.3 nm. The narrow FWHM is due to the small ionic radii of Sc³âº, which enhance the crystal field strength affecting the optical properties of Er³âº ions located at the well-defined lattice sites of Sc silicate. A large excitation cross-section (σ(ex)) is equal to 3.0x10⁻²° cm² at λ(ex) = 1527.6 nm.

Investigating the relative risk factors of injuries caused by accidents on roads in the mashhad area in 2007.

BACKGROUND: Currently, accidents are the second highest cause of death in most societies. Traffic accidents account for the largest proportion of accidental deaths. The aim of this report was to identify the accidents that cause casualties on the roads around Mashhad. METHODS: This study was a case-control study, where the cases were drivers who had accidents resulted in casualties, and the controls were drivers who had accidents in the same locations without casualties. Variables included age, sex, seatbelt use, spontaneous combustion, entrapment within the vehicle, ejection from the vehicle, music playing in the vehicle at the time of the accident, use of cell phone, smoking at the time of the accident, the direction of the accident, the time of day, and the model of the vehicle. RESULTS: Interviews were conducted with the 90% of the cases and the 93% of the controls who consented to being interviewed. Females accounted for 16.2% of the case group and 23.4% of the control group, and males comprised 83.8 % of the cases and 76.6% of the controls. The average age of the case group was 35.5±10.5 and of the control group was 39.4±9.8 years. The use of a seatbelt as a safety factor was significantly greater in the control group (OR=0.44). Combustion occurred in approximately 21% of the accidents in the case group, but in only 1.3% of the accidents in the control group. Being trapped in and being ejected from the vehicle were significantly more prevalent in the case group. CONCLUSIONS: According to the results of this study, the fastening of seatbelts had a significantly positive effect on reducing the injuries caused by an accident. Age was another significant indicator influencing the outcome of road accidents education through media seems to play a great role in reducing mortality and morbidity due to road accident.

First Report of Chickpea chlorotic stunt virus Infecting Legume Crops in Tunisia.

During a survey of legume crops in the northeast and northwest regions of Tunisia in April 2010, plants showing yellowing, reddening, and stunting symptoms were observed. A total of 281 symptomatic samples were collected: 142 plants from 10 chickpea (Cicer arietinum L.) fields, 84 plants from six faba bean (Vicia faba L.) fields, and 55 plants from six pea (Pisum sativum L.) fields. All samples were tested by the tissue-blot immunoassay procedure with the following monoclonal antibodies (MAbs): a broad-spectrum legume-luteovirus MAb (5G4), Faba bean necrotic yellows virus (FBNYV; genus Nanovirus, family Nanovirudae) (3-2E9; provided by J. Vetten, BBA, Braunschweig, Germany), Beet western yellows virus (BWYV; genus Polerovirus, family Luteoviridae) (A5977; Agdia, Elkhart, IN), Bean leafroll virus (BLRV; genus Luteovirus, family Luteoviridae) (4B10), Soybean dwarf virus (SbDV; genus Luteovirus, family Luteoviridae) (ATCC PVAS-650; American Type Culture Collection ATCC, Rockville, MD,), and a mixture of three MAbs (5-2B8, -3D5, and -5B8) to a Syrian isolate of Chickpea chlorotic stunt virus (CpCSV) (1). Serological tests showed that CpCSV was detected in 121 samples (43.06%) (62 chickpea, 57 faba bean, and 2 pea), followed by FBNYV (detected in three faba bean and three pea), BWYV (detected in three chickpea and one faba bean), and BLRV (detected in one pea sample). FBNYV, BLRV, and BWYV have been previously detected in faba bean and chickpea in Tunisia (4), but to our knowledge, this is the first report of CpCSV affecting legumes in Tunisia, which was found in seven chickpea, seven faba bean, and two pea fields. CpCSV has been reported to naturally infect legume crops such as chickpea, lentil, field pea, and faba bean as well as some leguminous weeds and a few wild non-legume plants species in many countries in West Asia and North Africa and causes economic losses on chickpea in Eritrea, Ethiopia, and Syria (1-3). Serological results of CpCSV was confirmed in four (two pea, one faba bean, and one chickpea) samples by reverse transcription (RT)-PCR using CpCSV specific primers (F:5'-TAGGCGTACTGTTCAGCGGG-3' and R:5'-TCCTTTGTCCATTCGAGGTGA-3') (3), which produced an amplicon of expected size (413 bp). No amplification was observed from healthy plant extracts. Sequence analysis revealed that the four Tunisian isolates (TuV 258-201 collected from faba bean [GenBank Accession No. HQ199310], TuC 215-201 collected from chickpea [HQ199307], and TuP 163-201 [HQ199308] and TuP 166-201 collected from pea [HQ199309]) were most similar to each other with a high sequence identity (99%) and clustered with isolates of CpCSV from Syria (GenBank Accession No. EU541270), Egypt (EU541269), and Morocco (EU541267), to which they were most closely related (98%). The Tunisian isolates also showed high sequence identity (96%) in the coat protein region with Ethiopian (GenBank Accession No. EU541257) and Sudanese (EU541263) isolates. However, all isolates are distinct from BWYV, BLRV, and SbDV (less than 70% sequence identity). Since CpCSV is transmitted by aphids only, additional studies are needed to identify the host range of the virus and the efficient aphid vectors to better understand the epidemiology of this virus under Tunisian conditions References: (1) A. D. Abraham et al. Arch.Virol. 154:791; 2009. (2) N. Y. Asaad et al. J. Phytopathol. 157:756, 2009. (3) S. G. Kumari et al. Phytopathol. Mediterr. 47:42, 2008. (4) A. Najar et al. Phytopathol. Mediterr. 39:423, 2000.

Motorcycle fatal accidents in khorasan razavi province, iran.

BACKGROUND: All over the world motorcycle accident are one of the major causes of road death and injury. This study aimed to determine the pattern of Motorcycle Fatal Accidents in Mashhad-Iran. METHODS: This descriptive cross-sectional study was carried out in 2006 to analyze the epidemiological pattern of the motorcycle accident in Mashhad, North-Eastern Iran. Three hundred fifty cases of motorcycle accidents were included. Data gathering tool was a standard questionnaire. The compiled data were analyzed using SPSS11 and χ(2) test. The significance level was considered 0.05 in all statistical tests. RESULTS: In the time span of the study, 350 cases of motorcycle accident occurred, most of which happened at 8pm to 12pm. In 119 cases, the motorcyclist was the blameful rider. Generally, 84.2% of the motorcycle riders did not have safety helmets. About two third of blameful motorcycle riders (63.1%) were less than 25 years old. The major cause of the accidents (55.1%) was due to neglecting the Yield Right of Way. Motorcycle riders endanger pedestrian, other drivers, passengers and their own life. CONCLUSION: Paying attention to cultural and instructional issues of correct motorcycle riding and performing appropriate monitoring in traffic and transportation system such as honoring our and others safety and setting limitations on using this vehicle by the youth is of great importance.

First Report of Beet mosaic virus Infecting Chickpea (Cicer arietinum) in Tunisia.

Chickpea plants with severe yellowing and tip wilting were observed in the Cap-Bon Region of Tunisia in 2006. The viral-like symptoms resulted in yield loss of approximately 25% in some fields. A total of 110 symptomatic chickpea plants was collected from nine chickpea fields and tested at the Virology Laboratory of ICARDA, Syria for eight legume viruses using tissue-blot immunoassay (TBIA) (3). Polyclonal antisera produced at the ICARDA Virology Laboratory were used to test for Chickpea chlorotic dwarf virus (genus Mastrevirus, family Geminiviridae), Broad bean stain virus (genus Comovirus, family Secoviridae), Broad bean mottle virus (genus Bromovirus, family Bromoviridae), and Bean yellow mosaic virus and Pea seed borne mosaic virus (genus Potyvirus, family Potyviridae). Antiserum to Beet mosaic virus (BtMV; genus Potyvirus, family Potyviridae) (AS-0143) was provided by the German Collection of Microorganisms and Cell Cultures (DSMZ, Braunschweig, Germany). In addition, three monoclonal antibodies (MAb) were used to detect Faba bean necrotic yellows virus (FBNYV; genus Nanovirus, family Nanoviridae) (MAb 3-2E9) (1), potyviruses (PVAS-769 [MAb PTY 3 Potyvirus Group] American Type Culture Collection, Manassas, VA), and luteoviruses (MAb B-2-5G4) (2). Twenty-two of the plants tested positive with MAb PTY 3 and BtMV antisera, 56 samples reacted with MAb B-2-5G4, and eight plants with the FBNYV MAb, whereas 24 plants tested negative with all antisera. Because reactions with the BtMV antiserum were unexpected, detection of BtMV was confirmed by reverse transcription-(RT)-PCR assays using BtMV-specific primers (LN26 and LN27) (4), which produced an amplicon of expected size (1,050 bp) from all plants that reacted with BtMV antiserum but not from plants that were serologically negative. Leaf tissue from a BtMV-infected plant was ground in 0.01 M potassium phosphate buffer, pH 7.2 (1:20, wt/vol), mixed with 0.5% celite, and used for mechanical inoculation of chickpea seedlings (cv. Beja 4). In addition, adults of three legume aphid species (Aphis craccivora, A. fabae, and Acyrthosiphon pisum) were starved for 1 h before feeding on BtMV-infected chickpea leaves for an acquisition access period of 5 min. Fifteen aphids of each species were placed on each chickpea plant, allowed to feed for 24 h, and then sprayed with an insecticide. Tip wilting symptoms appeared on plants 15 to 20 days after mechanical and aphid inoculations but not on plants used as negative control treatments (inoculated mechanically with healthy leaf tissue or with aphids that had fed on noninfected chickpea plants). Use of BtMV antiserum for TBIA analysis of inoculated plants revealed systemic BtMV infections in 35 of 92 plants inoculated mechanically and 15 of 75 plants inoculated with viruliferous A. fabae only. To our knowledge, this is the first record of BtMV infecting chickpea in Tunisia. References: (1) A. Franz et al. Ann. Appl. Biol. 128:255, 1996. (2) L. Katul. Characterization by serology and molecular biology of bean leaf roll virus and faba bean necrotic yellows virus. Ph.D. thesis. University of Gottingen, Germany, 1992. (3) K. M. Makkouk and A. Comeau. Eur. J. Plant Pathol. 100:71, 1994. (4) L. G. Nemchinov et al. Arch. Virol. 149:1201, 2004.

[Erectile dysfunction after radical prostatectomy : patient information, contact persons, postoperative proerectile therapy]. / Erektile Dysfunktion nach radikaler Prostatektomie : Aufklärung, Ansprechpartner, postoperative proerektile Therapie.

BACKGROUND: Postoperative erectile dysfunction (ED) is one of the potential after-effects of radical prostatectomy. The aim of this study was to learn which caregivers inform the patients prior to the intervention about the risk of ED, which individuals the patients discuss this issue with, and whether the patients preoperatively consider use of a PDE5 inhibitor for proerectile therapy after the operation. METHODS: Using the IIEF-5 questionnaire, the preoperative erectile function of 110 patients was evaluated after the hospital admission interview. The patients were asked who had informed them about the risk of postoperative ED. They were also asked in whom they had confided to discuss this issue and whether they were prepared to undergo postoperative proerectile therapy with a PDE5 inhibitor. The patients were subsequently assigned to one of two groups: group I, consisting of those with a preoperative IIEF score > or = 21, or group II, those with a preoperative IIEF score <21. RESULTS: The answers given by groups I and II did not differ significantly. The median patient age was the same, 68, in both groups. In addition to being informed about postoperative ED by the hospital doctor on admission (100%), the patients were informed about this by the following individuals (results for group II in parentheses): board-certified urologist, 81.8% (74%); general practitioner (GP), 27.3%; partner, 12.1% (11.7%); self-help groups, 0% (2.6%); and friends, 3% (6.5%). Patients also discussed the risk of postoperative ED with the following individuals (results for group II in parentheses): local urologist, 66.7% (63.4%); partner, 45.5% (42.9%); hospital doctor, 39.4% (42.9%); GP, 21.2% (23.4%); friends, 9.1% (14.3); or no one, 3% (5.2%). Regarding whether patients were willing to undergo postoperative therapy using a PDE5 inhibitor, 36.4% in group I and 32.5% in group II said yes, 12.1% in group I and 11.7% in group II said no, and 51.5% in group I and 55.8% in group II were undecided. CONCLUSION: Irrespective of the patient's erectile status, the hospital doctor and the local urologist informed the patients about the risk of postoperative ED. Satisfactory information delivered by at least two people occurred in over 70% of all cases. The most frequent confidant of the patient for discussing this issue was his local urologist. Fewer than 50% of the patients discussed this topic with their partners. Possible reasons for underestimating the importance of sexual function could be the frequent taboo status of sexuality as a discussion topic in relationships, as well as preoperative distress. These circumstances should be taken into account by offering sufficient information, including that on the availability of postoperative proerectile therapy, for both the patient and his partner as early as possible, i.e., at the stage of choosing a treatment option.

[30 Years of sentinel lymph node diagnostic in penile carcinoma: development of a diagnostic procedure and current results]. / 30 Jahre Sentinel-Lymphknotendiagnostik beim Peniskarzinom : Evolution eines diagnostischen Verfahrens und eigene aktuelle Ergebnisse.

Cabanas, working 30 years ago, was the first to use the term "sentinel lymph node" in urology. His definition of the sentinel lymph node was based on typical anatomical patterns and therefore could not do justice to any individual variability in lymphatic drainage. This meant that application of the technique yielded high false-negative rates, and because of this it was largely abandoned. Dynamic visualization of lymphatic drainage by blue dye in melanoma patients resulted in a renaissance of the sentinel node concept in penile cancer in the mid-1990s. With constant improvements and standardization of the technique it proved possible to reduce the incidence of false-negative results from the initial 22% to 4.8%. This technique requires that specialists in urology, pathology, and nuclear medicine collaborate closely, and high standards are also essential in quality control.

Viroid Prevalence in Tunisian Citrus.

The citrus industry in Tunisia is based mainly on the production of local cultivars of sweet orange (Citrus sinensis), common mandarin (C. reticulata), clementine (C. clementina), and lemon (C. limon). Sour orange (C. aurantium) is the only rootstock presently being used in the major growing area located at Cap Bon where 80% of citrus is being produced. The presence of tristeza disease in the Mediterranean basin is a threat to the Tunisian citrus industry, and new rootstocks giving tristeza tolerant rootstock/scion combinations are urgently needed as an alternative to sour orange. Since some promising rootstocks are known to be sensitive to viroids (1), a survey was conducted to determine if the cultivars grown presently in Tunisia were infected with viroids. Following a preliminary report (2), an extensive survey was conducted from 1995-2001 that included 174 symptomless sources being grown at Cap Bon: 26 Maltaise demi-sanguine, 9 Maltaise sanguine, 20 Maltaise blonde, 4 orange doublefine, 16 Washington navel, 12 Valencia late, 29 common mandarin, 42 Cassar clementine, 5 Lunari lemon, and 11 Eureka lemon. These sources were graft-inoculated into Etrog citron that subsequently developed symptoms characteristic of viroid infection. Sequential polyacrylamide gel electrophoresis analysis and molecular hybridization using viroid-specific probes (1) revealed that all sources were infected with at least two viroids. Citrus exocortis viroid (CEVd), Hop stunt viroid (HSVd), and Citrus viroid III (CVd-III) were widespread and accounted for 68.4, 67.8, and 81.0% of the sources tested, respectively. Citrus bent leaf viroid (CBLVd) and Citrus viroid IV (CVd-IV) were only found in 32.7 and 2.3% of the sources. The most frequent viroid combinations were CEVd+HSVd+CVd-III (17.8%) and CEVd+CVd-III (17,2%), whereas HSVd+CVd-IV and CEVd+CBLVd+CVd-III+CVd-IV were found in a single source (0.6%). References: (1) N. Duran-Vila and J. S. Semancik. Pages 178-194 in: Viroids. CSIRO Publishing, Australia, 2003. (2) A. Najar et al. Pages 398-400 in: Proc. 15th Conf. Int. Org. Citrus Virol, 2002.

Adhesion of a glass-ionomer root canal sealer to human dentine.

This in vitro study evaluated the effect of smear layer removal on adhesion to human dentine of Ketac-Endo, Grossman, and Sealer 26 root canal sealers. A total of 60 extracted human maxillary and mandibular molars with their crowns ground flat were used. The teeth were divided into two groups: Group 1, the dentine surface received no treatment; Group 2, EDTA-C was applied to the dentine surface for 5 min. Ten samples were tested for each sealer and each group. Adhesion was measured with a Universal Testing Machine. Sealer 26 showed greater adhesion both with and without smear layer (p < 0.01). Ketac-Endo and Grossman sealers were statistically equal, having the lowest values of adhesion. Application of EDTA-C did not alter the adhesion of Ketac-Endo and Grossman sealers. However, the use of EDTA-C increased the adhesion of Sealer 26. The epoxy resin-based root canal sealer (Sealer 26) adhered better to dentine prepared with and without EDTA-C than glass-ionomer-based sealers and the zinc oxide eugenol-based (Ketac-Endo and Grossman) sealers.

Hernia crural. Resultados tras 10 años de tratamiento mediante plug de Lichtenstein / Femoral hernia: result after ten years of employing Lichtenstein's plug

Introducción. Desde el año 1989 utilizamos la técnica descrita por Lichtenstein para el tratamiento de la hernia crural. Con el objetivo de evaluar los resultados de la técnica, se han incluido todos los pacientes en el presente estudio. Pacientes y métodos. Se estudian prospectivamente 224 pacientes (228 herniorrafias) intervenidos entre junio de 1989 y junio de 1999; 178 fueron mujeres (79,4 por ciento). La edad media fue de 57,7 años (rango, 16-98). La intervención fue urgente en el 32,9 por ciento de los casos, y el 5,3 por ciento de éstos necesitó resección intestinal. Se empleó anestesia general en 161 casos (70,5 por ciento), regional en 58 (25,6 por ciento), y local en 9 (3,9 por ciento). Se utilizó polipropileno monofilamento en todos los casos. El seguimiento medio mediante exploración periódica es de 57 meses (rango, 1-120). Resultados. La estancia media fue de 3,5 días. Se produjeron complicaciones locales en 15 casos (6,6 por ciento), e intolerancia a la prótesis en un caso (0,4 por ciento); un paciente (0,4 por ciento) precisó reintervención por protrusión de la malla con dolor persistente; una hernia (0,4 por ciento) recidivó; una paciente (0,4 por ciento) intervenida de urgencia falleció; 3 pacientes (1,3 por ciento) han presentado posteriormente hernia inguinal del mismo lado. Conclusiones. Creemos que la herniorrafia crural con prótesis cilíndrica es la técnica de elección en la hernia crural, si bien en los casos de hernia recidivada o incarcerada pueden contemplarse otras alternativas (AU)

[Pregnancy rate in cryopreserved embryos based on the classical morphologic scoring and the integrity of blastomeres at thawing]. / Tasa de embarazo en embriones criopreservados según la calificación morfológica clásica y la integridad de las blastómeras a la descongelación.

Two different thaw embryo classifications were evaluated, the morphologic classic evaluation (Veeck, 1990) and all blastomeres intact at the time of embryo transfer. We also discuss the clinic parameters and the physiopathological causes implicated in the successful of this treatment. 176 ovarian stimulation cycles and 513 cryopreserved embryos were reviewed. We found better pregnancy rate and delivery rate in embryo transfers were at least one embryo had all blastomeres intact compare with the transfers with good quality embryos (1+, 2+) of the morphologic classic evaluation without statistic significance (p > 0.05). Pregnancy and delivery rate were higher in cases with embryo in pronuclear stage compare with cleavage stage (p < 0.05). The blastomeric harm disturbs the embryo implantation phase and the future is oriented to the microsurgical remove of the damaged blastomeres and the use of assisted hatching.

Hernia inguinal recidivada: tratamiento mediante abordaje preperitoneal y prótesis amplia de malla de polipropileno / Recurrent inguinal hernia: treatment involving the preperitoneal approach and placement of a large sheet of prosthetic polypropylene mesh

Introducción. El objetivo del presente trabajo es evaluar los resultados de la reparación de las hernias recidivadas de la región inguinal mediante abordaje preperitoneal y colocación de una prótesis amplia de malla de polipropileno, siguiendo las técnicas descritas por Nyhus y Stoppa. Pacientes y método. Se estudian prospectivamente 72 pacientes tratados de 76 hernias recidivadas de la región inguinal (74 inguinales y 4 crurales) mediante esta técnica, entre marzo de 1990 y diciembre de 1998. En 8 casos (4 pacientes) la hernia fue bilateral. El número de intervenciones previas osciló entre 1 y 4. Se comentan aspectos técnicos. Resultados. El período de seguimiento oscila entre 2 meses y 8,7 años (media 3,9 años). Las complicaciones observadas han sido: infección de la herida en un 2,6 por ciento (n = 2), seroma en un 1,3 por ciento (n = 1) e íleo en un 1,3 por ciento (n = 1). No se han presentado complicaciones hemorrágicas, intolerancia a la malla, ni orquitis isquémica. Tampoco ha habido mortalidad postoperatoria y hasta el momento no se ha producido ninguna recidiva. Conclusiones. Con el abordaje preperitoneal y la colocación de una malla de polipropileno monofilamemto se obtienen unos buenos resultados que nos permiten considerar esta técnica como de elección en el tratamiento de las hernias recidivadas de la región inguinal (AU)

Metástasis pancreática de adenocarcinoma renal / Pancreatic metastasis from renal adenocarcinoma

Presentamos un caso de metástasis pancreática de adenocarcinoma renal en una paciente intervenida hacía 14 años por un adenocarcinoma renal, en la revisión de su enfermedad se objetivó, en la ecografía y en la TAC, un nuevo adenocarcinoma renal en el riñón contralateral con un nódulo en cuerpo pancreático, siendo éste una metástasis de adenocarcinoma renal, que se confirmó con la PAAF. Se realizó una nefrectomía parcial y una resección corporocaudal pancreática por lumbotomía, no siendo el abordaje de elección pero permitiendo un buen campo para la resección pancreática parcial. Tras 20 meses de seguimiento, la paciente presenta una remisión total de su enfermedad (AU)

First Record of Barley yellow striate mosaic virus, Barley stripe mosaic virus, and Wheat dwarf virus Infecting Cereal Crops in Tunisia.

A survey conducted during April 2000 to identify viruses infecting cereal crops in different regions (Beja, Bizerte, Cap-bon, Jendouba, Kairouan, Siliana, and Zaghouan) of Tunisia covered 15 barley, 21 durum wheat, and 7 bread wheat randomly selected fields. Virus incidences were determined on the basis of laboratory testing of 100 to 200 randomly collected samples from each field. A total of 5,227 random (1,654 barley, 2,546 durum wheat, and 1,027 bread wheat) and 1,430 symptomatic (451 barley, 746 durum wheat, and 233 bread wheat) samples were collected. Samples were tested for the presence of five different viruses by tissueblot immunoassay (TBIA) (1) at the Virology Laboratory of INRAT. Antisera used were for Barley stripe mosaic virus (2), Barley yellow dwarf virus (PAV serotype) (2), Wheat streak mosaic virus (3), Barley yellow striate mosaic virus (BYSMV) provided by E. Luisoni, IFA, Turino, Italy (4), and Wheat dwarf virus (WDV) provided by J. Vacke, Research Institute of Crop Production, Prague, Chech Republic. BYDVPAV was detected in seven barley (from three fields), 25 durum wheat (10 fields), and eight bread wheat (three fields) samples from all except the Siliana region. BYSMV was detected in three barley (three fields), 16 durum wheat (six fields), and four bread wheat (three fields) samples from the Beja, Bizerte, Cap-bon, Jendouba, and Siliana regions. WDV was detected in five barley (three fields), nine durum wheat (four fields), and four bread wheat (one field) samples from the Beja, Cap-bon, and Bizerte regions. BSMV was detected in 49 barley (six fields) and 25 durum wheat (five fields) samples from the Beja, Bizerte, Cap-bon, Kairouan, and Zaghouan regions. This is the first record of BYSMV, BSMV, and WDV infecting cereal crops in Tunisia, but their incidence in fields was less than 1%. However, BSMV incidence was 10.5% in one barley field from the Cap-bon region. Virus incidence in symptomatic plants was a bit higher and ranged from 0.8% for WDV in bread wheat to 6% for BSMV in barley. References: (1) K. M. Makkouk and A. Comeau. Eur. J. Plant Pathol. 100:71, 1994. (2) K. M. Makkouk and S. G. Kumari. Rachis Newsl. 12(1/2):24, 1993. (3) K. M. Makkouk and S. G. Kumari. Rachis Newsl. 16(1/2):74, 1997. (4) R. G. Milne et al. Intervirology 25:83, 1986.

[Embryonic quality in the use of urofolitropin vs recombinant FSH for in vitro fertilization]. / Calidad embrionaria en la utilización de urofolitropina vs FSH recombinante para fertilización in vitro.

There were no differences in both groups as tho the age of the patients; received doses of both types of FSH, nor HMG; but there was as to the amount of captured ovocytes, amount, and quality, embrionary, in special 1+ 2+ in favor of the group that received urofolitropine, specially under 35 years of age. In this study there was better qualy and amount, embrionary, obtained with the use of urofolitropine, as compared with FSH recombinant for in vitro fertilization.