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J Toxicol Environ Health A ; 79(8): 367-75, 2016.
Article in English | MEDLINE | ID: mdl-27142484

ABSTRACT

The aim of this study was to determine the presence of Asian dust particles (ADP) in patients suffering from conjunctivitis and its correlation with clinical scores for conjunctivitis. Forty-five patients from the Fukuoka area who were newly diagnosed acute conjunctivitis were selected. The degrees of inflammatory reaction, itchy sensation, hyperemia, eye discharge, and foreign body sensation were clinically recorded and scored. Eyes were washed with physiological solution. Solid particles collected from the washing solution were observed using a scanning electron microscope. Of the 45 samples, 44 were positive for the elements silicon (Si) and aluminum (Al), which are components of ambient Asian dust. Higher conjunctivitis scores were found in the subgroup in which the Asian dust/whole particle ratio was greater than average. This is the first apparent report on the correlation between amount of ADP exposure at the ocular surface and severity of ocular symptoms.


Subject(s)
Conjunctivitis/chemically induced , Dust , Eye/pathology , Particulate Matter/toxicity , Acute Disease , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Conjunctivitis/etiology , Conjunctivitis/immunology , Female , Humans , Japan , Male , Middle Aged , Young Adult
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