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1.
Arq Bras Cardiol ; 84(2): 108-10, 2005 Feb.
Article in Portuguese | MEDLINE | ID: mdl-15761631

ABSTRACT

OBJECTIVE: To assess the prevalence of coronary artery disease (CAD) in a population of type I diabetic, nephropathic patients in a dialysis program and candidates for double transplantation (kidney and pancreas). METHODS: From January 2000 to July 2002, 58 type I diabetic patients underwent coronary cineangiography as part of an assessment protocol for double transplantation. Coronary artery disease was defined as any irregularity in the coronary arteries and was classified according to the degree of luminal stenosis as mild (< 30%), moderate (> or = 30 to 70%), and severe (> 70%). RESULTS: The mean age of the patients was 34 +/- 12 years, and 32 (55%) were men. No patient had a history of angina or acute myocardial infarction. The major risk factors for the disease were systemic arterial hypertension in 93% of the patients, dyslipidemia in 38%, familial history in 25%, and smoking in 20%. The mean duration of diabetes was 20.8 +/- 9 years, and the duration of dialysis was 26 +/- 9 months. Coronary angiography revealed coronary artery disease in 42 (72%) patients, which was mild in 20 (34%) patients, moderate in 9 (16%), and severe in 13 (22%). CONCLUSION: Patients with type I diabetes in a dialysis program and candidates for double transplantation had an elevated prevalence of coronary artery disease. It is worth noting that those patients had no symptoms of the disease.


Subject(s)
Coronary Artery Disease/etiology , Diabetes Mellitus, Type 1/complications , Diabetic Nephropathies/complications , Kidney Transplantation , Pancreas Transplantation , Adult , Coronary Angiography , Coronary Artery Disease/diagnosis , Coronary Artery Disease/epidemiology , Female , Humans , Male , Middle Aged , Patient Selection , Prevalence , Retrospective Studies , Risk Factors , Severity of Illness Index
2.
Arq. bras. cardiol ; 84(2): 108-110, fev. 2005.
Article in Portuguese | LILACS | ID: lil-393665

ABSTRACT

OBJETIVO: Avaliar a prevalência da doença arterial coronariana (DAC) em população de pacientes diabéticos tipo 1, nefropatas, em programa de diálise e candidatos a transplante duplo (rim e pâncreas). MÉTODOS: De janeiro/2000 a julho/2002, foram submetidos a cinecoronariografia, como protocolo de avaliação para transplante duplo, 58 pacientes diabéticos tipo 1. Doença arterial coronariana foi definida como qualquer irregularidade nas artérias coronárias, e classificada, de acordo com a grau de estenose luminal, em leve (<30 por cento), moderada (>30 a 70 por cento) e grave (>70 por cento). RESULTADOS: A idade dos pacientes foi 34 ± 12 anos, sendo que 32 (55 por cento) eram homens. Nenhum paciente tinha história de angina ou infarto agudo do miocárdio. Os principais fatores de risco para a doença foram hipertensão arterial sistêmica em 93 por cento, dislipidemia em 38 por cento, historia familiar em 25 por cento e tabagismo 20 por cento. O tempo médio de duração do diabetes foi 20,8 ± 9 anos, o tempo de diálise de 26 ± 9 meses. A coronariografia revelou doença arterial coronariana em 42 (72 por cento) pacientes, sendo 20 (34 por cento) discreta, 9 (16 por cento) moderada e 13 (22 por cento) grave. CONCLUSÃO: Pacientes diabéticos tipo 1 em programa de diálise e candidatos a transplante duplo têm elevada prevalência de doença arterial coronariana, tornando-se marcante a observação de que esses pacientes não apresentavam sintomas da doença.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Coronary Artery Disease/etiology , Diabetes Mellitus, Type 1/complications , Diabetic Nephropathies/complications , Kidney Transplantation , Pancreas Transplantation , Coronary Angiography , Coronary Artery Disease/diagnosis , Coronary Artery Disease/epidemiology , Patient Selection , Prevalence , Retrospective Studies , Risk Factors , Severity of Illness Index
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