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2.
Neurol Res ; 22(6): 583-7, 2000 Sep.
Article in English | MEDLINE | ID: mdl-11045020

ABSTRACT

The spontaneous disappearance and reappearance of a ruptured cerebral aneurysm is generally assumed to be a rare phenomenon although the actual incidence is unknown. Among 39 consecutive cases of acute subarachnoid hemorrhage (SAH), 33 were studied by three-dimensional computed tomographic angiography (CTA) within 6 h after the onset of SAH, followed by digital subtraction angiography (DSA) within 24 h after the ictus. Of those patients, one, a 58-year-old woman, had a saccular aneurysm at the distal anterior cerebral artery; the aneurysm was clearly demonstrated by CTA 2.5 h after the SAH onset, but was not shown by a subsequent DSA performed 8.5 h after the ictus. A follow-up DSA detected the neck of aneurysm on day 11, and the whole aneurysm was visualized on day 19. The observations in this particular case suggest that the spontaneous disappearance of a ruptured cerebral aneurysm may occur during the ultra-early stage of SAH and that reappearance may follow during the next few weeks. The patient did not suffer complications such as vasospasm or systemic hypotension nor was she treated with antifibrinolytic agents. The aneurysmal shape and the surrounding clot are considered as putative factors possibly related to the intermittent appearance of the aneurysm.


Subject(s)
Aneurysm, Ruptured/physiopathology , Intracranial Aneurysm/physiopathology , Subarachnoid Hemorrhage/diagnostic imaging , Aneurysm, Ruptured/diagnostic imaging , Cerebral Angiography , Female , Humans , Image Processing, Computer-Assisted , Intracranial Aneurysm/diagnostic imaging , Male , Middle Aged , Recurrence , Remission, Spontaneous , Subarachnoid Hemorrhage/physiopathology , Tomography, X-Ray Computed
3.
J Neurosurg ; 92(4): 697-701, 2000 Apr.
Article in English | MEDLINE | ID: mdl-10761662

ABSTRACT

The authors present a rare case of a giant intracranial mucocele associated with an orbitoethmoidal osteoma in a patient suffering from a generalized convulsive disorder. The broad pedicle of the osteoma had penetrated the cribriform plate and extended intracranially to form a nodular mass in the olfactory groove. The intracranial portion of the osteoma was surrounded by a mucocele. Both the cyst wall and multilayered intracystic septations of the mucocele were indented by layers of the osteoma. Although the extracranial portion adhered to the mucosa of the ethmoidal sinus, there were no signs of sinus obstruction. No direct communication other than the osteoma was identified between the mucocele and the ethmoidal mucosa. The large cerebral defect, which the mucocele occupied, communicated directly with the lateral ventricle without any intervening membranous structures. A frontal craniotomy is recommended for exposure of the lesion and plastic repair of the dural defect.


Subject(s)
Brain Diseases/complications , Ethmoid Sinus/pathology , Mucocele/complications , Orbital Neoplasms/complications , Osteoma/complications , Paranasal Sinus Neoplasms/complications , Brain Diseases/surgery , Craniotomy/methods , Dura Mater/surgery , Ethmoid Sinus/surgery , Humans , Lateral Ventricles/pathology , Male , Middle Aged , Mucocele/surgery , Mucous Membrane/pathology , Orbital Neoplasms/surgery , Osteoma/surgery , Paranasal Sinus Neoplasms/surgery , Seizures/etiology
4.
Proc Natl Acad Sci U S A ; 92(4): 1038-42, 1995 Feb 14.
Article in English | MEDLINE | ID: mdl-7862629

ABSTRACT

Male-released sex pheromone constituents of the longhorn beetle Anaglyptus subfasciatus (Coleoptera: Cerambycidae) are identified by GC-MS and GC-Fourier transform infrared as a 7:1 molar mixture of 3-hydroxy-2-hexanone and 3-hydroxy-2-octanone. These two compounds undergo thermal isomerization during GC analyses to give the corresponding 2-hydroxy-3-alkanones. Comparison of GC retention times of the natural products with those of synthesized enantiomerically pure compounds revealed that both semiochemicals have (R)-stereochemistry. These absolute configurations were confirmed by comparisons of the (R)-methoxy(trifluoromethyl)phenylacetic acid esters of insect-derived and synthetic samples.


Subject(s)
Coleoptera/chemistry , Hexanones/chemistry , Ketones/chemistry , Sex Attractants/chemistry , Animals , Chromatography, Gas/methods , Electrochemistry , Female , Flame Ionization , Hot Temperature , Isomerism , Male , Molecular Structure , Stereoisomerism
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