ABSTRACT
Our patient, an 83-year-old man, suddenly experienced acute lumbago and was prescribed bed rest. Later, pneumonia was diagnosed, even though he had no predisposing illness, and endophthalmitis developed in both eyes. Cultures of anterior chamber and vitreous specimens were positive for group B streptococcus. Treatment with systemic antibiotics, to which this bacteria is sensitive, was begun and his condition gradually improved. Nevertheless, the patient became blind in his right eye and the eye was enucleated. Histopathologic examination showed metastatic endophthalmitis with retinal detachment. Multiple microabscesses were found in the thickened choroid. We speculated that organisms disseminating from the microabscesses had caused the metastatic endophthalmitis.
Subject(s)
Endophthalmitis/microbiology , Eye Infections, Bacterial/microbiology , Streptococcal Infections/microbiology , Streptococcus agalactiae/isolation & purification , Aged , Aged, 80 and over , Anterior Chamber/microbiology , Anti-Bacterial Agents , Drug Therapy, Combination/therapeutic use , Endophthalmitis/pathology , Endophthalmitis/therapy , Eye Enucleation , Eye Infections, Bacterial/pathology , Eye Infections, Bacterial/therapy , Follow-Up Studies , Humans , Male , Pneumonia, Bacterial/microbiology , Pneumonia, Bacterial/pathology , Pneumonia, Bacterial/therapy , Streptococcal Infections/pathology , Streptococcal Infections/therapy , Vitreous Body/microbiologyABSTRACT
We treated a 65-year old woman with diffuse uveitis and an intraocular mass. The diffuse uveitis resolved with the administration of corticosteroids, but the intraocular mass did not respond to treatment. A transscleral biopsy of the lesion was performed. Histopathological study revealed non-Hodgkin's large-cell lymphoma. Immunohistochemical analysis showed that the tumor cells were derived from B-cells. The intraocular mass diminished after radiation therapy. The transscleral biopsy proved useful in establishing the correct diagnosis.
