[Placental morphometric characteristics in women who have experienced mono- and mixed viral respiratory infections during pregnancy]. / Morfometricheskaia kharakteristika platsenty u zhenshchin, perenesshikh mono- i mikstvirusnuiu respiratornuiu infektsiiu v period beremennosti.

OBJECTIVE: To study placental morphometric parameters in women who have experienced mono- and mixed viral respiratory infections during pregnancy. SUBJECT AND METHODS: Three groups of placentas were studied. Group 1 consisted of 25 placentas from women with physiological pregnancy; Group 2 included 25 placentas from those who had experienced parainfluenza type 3; and Group 3 comprised 25 placentas from those who had mixed respiratory viral infection (parainfluenza type 3 concurrent with influenza A (H3N2)) in the second trimester of pregnancy. The weight of the placenta and its morphometric parameters were determined on hematoxylin and eosin stained tissue sections using a square multifaceted stereometric grid placed in the microscopic eyepiece (magnification 15×20). RESULTS: Group 3 versus Group 2 exhibited a reduction in placental weights along with an increase in the stroma, fibrinoid around the villi and in the stroma, pseudonecroses, calcification, intermediate immature villi, small avascular villi, and hemorrhages in the intervillous space and a decrease the volume of the circulatory bed. CONCLUSION: In women in the second trimester of pregnancy, mixed viral respiratory infection has a more pronounced negative impact on the formation of the placenta.

[Regional characteristics of pulmonary ventilation and hemodynamics in pregnant women suffering from chronic bronchitis]. / Regional'nye osobennosti ventiliatsii i gemodinamiki v legkikh u beremennykh zhenshchin, stradaiushchikh khronicheskim bronkhitom.

Altogether 96 normal women and 82 women with chronic nonobstructive bronchitis were examined during pregnancy using zonal rheography of the lungs. It was established that in pregnant women afflicted with chronic nonobstructive bronchitis, the regional ventilation and hemodynamics of the pulmonary circulation underwent rearrangement. It was discovered that in the second half of pregnancy there develop the signs of latent respiratory insufficiency manifesting themselves in an increase of the rheographic parameters of the ventilation perfusion relations. The regression equation is offered to calculate the proper values of the ventilation/blood flow ratio depending on the time of pregnancy.