ABSTRACT
The aim of our study was the investigation of toxicity of denture prosthetic appliance Prothyl Hot on the model system of Jurkat cell culture. As a result of our study it was revealed that denture prosthetic appliance Prothyl Hot: - hadn't manifested toxic effects the viability Jurkat cells (that reviled by stability of activity of mitochondrial dehydrogenises and mean of mitochondrial membrane potential; - didn't influence on the balance of pro-and antyinflammatory cytokines, expressed by Jurkat cells; - induces intensification of oxidative metabolism in Jurkat cells, which may be considered as compensatory reaction developing in the cells.
Subject(s)
Dental Materials/adverse effects , Dentures/adverse effects , Apoptosis/drug effects , Catalase/metabolism , Cytokines/metabolism , Glutathione Reductase/metabolism , Humans , Jurkat Cells , Membrane Potential, Mitochondrial/drug effects , Oxidative Stress , Superoxide Dismutase/metabolism , T-Lymphocytes/drug effectsABSTRACT
The aim of the work was estimation of perolar mucolytic agents in treatment of inflammatory diseases of middle ear and paranasal sinusitis. On the basis of research it was concluded that Sinupret reduced the necessity of grommet. Sinupret is the best systemic mucolytic in the treatment of inflammatory disease of middle ear and paranasal sinuses. To treat seros otitis media Sinupret was used as a monotherapy drug. In treatment of acute otitis media and sinusitis Sinupret is recommended in the third period of disease in combination with antibiotics.
