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Georgian Med News ; (192): 87-92, 2011 Mar.
Article in Russian | MEDLINE | ID: mdl-21525545

ABSTRACT

The aim of our study was the investigation of toxicity of denture prosthetic appliance Prothyl Hot on the model system of Jurkat cell culture. As a result of our study it was revealed that denture prosthetic appliance Prothyl Hot: - hadn't manifested toxic effects the viability Jurkat cells (that reviled by stability of activity of mitochondrial dehydrogenises and mean of mitochondrial membrane potential; - didn't influence on the balance of pro-and antyinflammatory cytokines, expressed by Jurkat cells; - induces intensification of oxidative metabolism in Jurkat cells, which may be considered as compensatory reaction developing in the cells.


Subject(s)
Dental Materials/adverse effects , Dentures/adverse effects , Apoptosis/drug effects , Catalase/metabolism , Cytokines/metabolism , Glutathione Reductase/metabolism , Humans , Jurkat Cells , Membrane Potential, Mitochondrial/drug effects , Oxidative Stress , Superoxide Dismutase/metabolism , T-Lymphocytes/drug effects
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