(18)F-FDG PET/CT imaging of critical ischemia in the diabetic foot.

A 72-year-old patient with type 2 diabetes mellitus underwent F-FDG PET/CT for diabetic foot infection. No increased focal uptake was seen. F-FDG uptake was absent in the second, third, and fourth toes of the right foot. Angiography demonstrated severe stenosis in the proximal anterior tibial artery and segmental stenosis on the posterior tibial artery. The patient was diagnosed as having dry gangrene of the second to fourth toes of the right foot due to ischemia. He underwent a selective amputation because of the lack of revascularization possibilities.

Assessment of the Stratos, a new pencil-beam bone densitometer: dosimetry, precision, and cross calibration.

The goal of this study was to assess a new pencil-beam densitometer, the Stratos (Diagnostic Medical Systems, Pérols, France). Evaluation of the dosimetry and precision were done together with an in vivo cross-calibration study performed with the fan beam densitometer Discovery A (Hologic, Bedford, MA). The results indicated that the Stratos performed bone mineral density (BMD) measurements with a good precision, low radiation dose, and good agreement with the Discovery A. The air dose, measured by an ionization chamber, was 40 µGy. The effective dose was assessed using an anthropomorphic phantom and thermoluminescent detectors resulting in 1.96 and 0.31 µSv for a lumbar spine and proximal femur scan, respectively. The average scattered dose rate at a distance of 1m from the device was 1.06 and 1.21 µSv.h(-1) in the lumbar spine and left proximal femur scan mode, respectively. For the precision evaluation, 30 patients underwent 2 lumbar spine and 2 proximal femur scans with repositioning after each scan. The percentage root-mean-square coefficient of variation was 1.22%, 1.38%, 2.11%, and 0.86% for the lumbar spine (L1-L4), lumbar spine (L2-L4), femoral neck, and total hip, respectively. The cross-calibration studies were done on 57 patients (60 ± 9 yr). Lumbar spine, left neck, and left total hip mean BMD were 3.10% lower and 11.94% and 8.83% higher, respectively, with the Stratos compared with the Discovery A. Cross-calibration equations were calculated with a correlation coefficient of 98% (p<0.01) for the lumbar spine (L2-L4), 94% (p<0.01) for the left neck, and 92% (p<0.01) for the left total hip. After standardizing the Stratos measures using the cross-calibration equations, LIN's concordance correlation coefficient was 0.98, 0.93, and 0.92 for the lumbar spine (L2-L4), left neck, and total hip, respectively.

Data acquisition analysis for femoral morphometric X-ray absorptiometry.

Bone mineral density (BMD) is a contributing factor of hip fracture risk. Other factors, such as lifestyle, the propensity for falls, and femoral geometry may influence the risk of hip fracture. The DMS Lexxos densitometer, a dual-energy X-ray densitometer can produce either a single-energy X-ray or a BMD image. The purpose of this study was to evaluate which of these 2 images enables the best detection to make femoral morphometry measurements. Spatial resolution, contrast, and noise were evaluated separately. A contrast-detail phantom was also used for the purpose of overall visual analysis. The spatial resolution was the same in the 2 images. The contrast was better with the BMD image, but the noise was higher. Using the contrast-detail phantom, the single-energy X-ray image allowed globally a better detection of the objects, but results were in the same range with high contrast values. Hip volunteers' morphometric measurements and the Singh Index were evaluated 3 times for each image by 3 observers, and the intra-, inter-, and global reproducibility was computed. The reproducibility of the measurements seems to be better with the single-energy X-ray image but results were not statistically significantly different. These results suggest that even if the image-quality indices were different, the single-energy X-ray image and BMD image are closely useful for clinical morphometric femoral evaluation.