1.
Med Parazitol (Mosk)
; (1): 23-6, 1994.
Article
in Russian
| MEDLINE
| ID: mdl-8015517
ABSTRACT
The effects of chloxyl and praziquantel on the lipid phase of erythrocytic membranes and the antioxidative system were studied in 77 patients with opisthorchiasis. After chloxyl treatment, patients with chronic opisthorchiasis had significantly higher contents of dienic conjugates, malonic dialdehyde, Schiff bases; in blood plasma, alpha-tocopherol content had a tendency to decrease. Treatment with praziquantel caused an increase in the content of malonic dialdehyde only in the erythrocytic membrane. Ten-day preadministration of vitamin E in a dose of 2 mg/kg body weight reduced the pro-oxidative action of praziquantel.