1.
Am J Cardiol
; 95(2): 236-40, 2005 Jan 15.
Article
in English
| MEDLINE
| ID: mdl-15642557
ABSTRACT
This study assessed the effects of tirofiban and statins on high-sensitivity C-reactive protein, interleukin-6, and soluble CD40 ligand after percutaneous coronary intervention in patients who had stable coronary artery disease. Tirofiban insignificantly limited the increase of soluble CD40 ligand after revascularization, especially in patients who had high levels of this marker at baseline (p = 0.06), whereas statins significantly inhibited increases in interleukin-6 and, to a lesser extent, high-sensitivity C-reactive protein without affecting the soluble CD40 ligand.
Subject(s)
Coronary Restenosis/prevention & control , Platelet Aggregation Inhibitors/administration & dosage , Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors , Tyrosine/analogs & derivatives , Tyrosine/administration & dosage , Angioplasty, Balloon, Coronary , C-Reactive Protein/metabolism , CD40 Ligand/blood , Coronary Artery Disease/blood , Coronary Artery Disease/therapy , Drug Therapy, Combination , Female , Humans , Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage , Infusions, Intravenous , Interleukin-6/blood , Male , Middle Aged , Prospective Studies , Tirofiban , Treatment Outcome
2.
Am J Cardiol
; 92(2): 236-9, 2003 Jul 15.
Article
in English
| MEDLINE
| ID: mdl-12860235