ABSTRACT
Oligodendrogliomas are rare glial tumors with a long natural history. Radical surgery, postoperative radiotherapy, chemotherapy and observation have been suggested as part of primary management. This series reports the presentation and outcome in 34 patients with histologically verified pure oligodendrogliomas treated between 1983 and 1993. All patients were treated at the time of initial diagnosis with surgery, with or without additional radiotherapy. The overall survival and progression free survival rates at five years were 69.8% and 55% respectively. There was no tumor or treatment related factor influencing survival significantly.
Subject(s)
Brain Neoplasms/physiopathology , Brain Neoplasms/surgery , Oligodendroglioma/physiopathology , Oligodendroglioma/surgery , Adolescent , Adult , Brain Neoplasms/radiotherapy , Child , Child, Preschool , Combined Modality Therapy , Female , Humans , Male , Middle Aged , Oligodendroglioma/radiotherapy , Survival AnalysisABSTRACT
In the past, many different surgical techniques have been proposed for treatment of the Chiari type I malformation. Despite the different technical considerations, in general, the treatment objectives have shared certain features: to prevent/ameliorate tonsillar crowding and to restore normal circulation of cerebrospinal fluid at the foramen magnum. We report a simple technique of coagulation of the herniated cerebellar tonsils in situ to decompress adjacent neural structures and to achieve the above-mentioned goals. When compared to the method of tonsillar resection, the procedure described herein affords the following two advantages: it is relatively less time-consuming and is more hemostatic. These two features minimize inflammation-mediated morbidity which may occur during the postoperative period.
Subject(s)
Arnold-Chiari Malformation/cerebrospinal fluid , Arnold-Chiari Malformation/surgery , Cerebellum/surgery , Adolescent , Humans , MaleABSTRACT
Temporary vascular occulsion during surgery for cerebral aneurysms has been slow to gain acceptance as an elective procedure. This study presents the outcome in 115 cases in whom temporary vascular occulsion was needed during aneurysmal surgery. Elective temporary clipping was used in 55 cases and emergency temporary vascular occulsion was performed in 60 cases. Judicious use of temporary clips did not increase the overall morbidity or mortality. Rescue temporary clipping as an emergency measure inthe face of intraoperative rupture has a deleterious effect as against elective use on the immediate as well as long term outcome of the patient. Use of elective temporary clipping in conjunction with adequate cerebral protective measures in advocated indifficult cases to facilitate definitive clipping of the aneurysm in order to improve the overall outcome.
