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1.
PLoS One ; 19(2): e0298550, 2024.
Article in English | MEDLINE | ID: mdl-38335156

ABSTRACT

After 2010, the source model of the microSelectron HDR Afterloader System was slightly modified from the previous model. Granero et al. named the modified source model "mHDR-v2r (revised model mHDR-v2)" and the previous model "mHDR-v2". They concluded that the dosimetric differences arising from the dimensional changes between the mHDR-v2 and mHDR-v2r designs were negligible at almost all locations (within 0.5% for r ≥ 0.25 cm), the two-dimensional anisotropy function difference between the two sources is found 2.1% at r = 1.0 cm when compared with the results of the other experimental group. To confirm this difference, we performed a full Monte Carlo simulation without energy-fluence approximation. This is useful near the radiation source where charged-particle equilibrium does not hold. The two-dimensional anisotropy function of the TG-43U1 dataset showed a few percent difference between the mHDR-v2r and mHDR-v2 sources. There was no agreement in the immediate vicinity of the source (0.10 cm and 0.25 cm), when compared to Granero et al. in mHDR-v2r sources. The differences in these two-dimensional anisotropy functions were identified.


Subject(s)
Brachytherapy , Brachytherapy/methods , Iridium Radioisotopes/therapeutic use , Radiotherapy Dosage , Monte Carlo Method , Radiometry/methods
2.
Igaku Butsuri ; 33(2): 82-7, 2013.
Article in Japanese | MEDLINE | ID: mdl-24575620

ABSTRACT

The outline of EGS5 code is described. History, scope (energy range and particle) of the simulation, major application of the code is mentioned. Physical processes in EGS5 code are described. Procedure to set up of input file and user code for new calculation is explained.


Subject(s)
Clinical Coding/standards , Computer Simulation , Monte Carlo Method , Radiometry/methods , Scattering, Radiation , Electrons , Health Physics , Particle Accelerators , Photons , Radiation Dosage , Radiation Protection/instrumentation , Radiometry/instrumentation , Radiotherapy Planning, Computer-Assisted
3.
Med Phys ; 39(10): 5910-6, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23039630

ABSTRACT

PURPOSE: A radiophotoluminescent glass rod dosimeter (RGD) has recently become commercially available. It is being increasingly used for dosimetry in radiotherapy to measure the absorbed dose including scattered low-energy photons on the body surface of a patient and for postal dosimetry audit. In this article, the dosimetric properties of the RGD, including energy dependence of the dose response, reproducibly, variation in data obtained by the RGD for each energy, and angular dependence in low-energy photons, are discussed. METHODS: An RGD (GD-301, Asahi Techno Glass Corporation, Shizuoka, Japan) was irradiated with monochromatic low-energy photon beams generated by synchrotron radiation at Photon Factory, High Energy Accelerator Research Organization (KEK). The size of GD-301 was 1.5 mm in diameter and 8.5 mm in length and the active dose readout volume being 1 mm diameter and 0.6 mm depth located 0.7 mm from the end of the detector. The energy dependence of the dose response and reproducibility and variation were investigated for RGDs irradiated with a plastic holder and those irradiated without the plastic holder. Response of the RGD was obtained by not only conventional single field irradiation but also bilateral irradiation. Angular dependence of the RGD was measured in the range of 0°-90° for 13, 17, 40, and 80 keV photon beams by conventional single field irradiation. RESULTS: The dose responses had a peak at around 40 keV. For the energy range of less than 25 keV, all dose response curves steeply decreased in comparison with the ratio of mass energy absorption coefficient of the RGD to that of air. As for the reproducibility and variation in data obtained by the RGD, the coefficient of variance increased with decrease in photon energy. Furthermore, the variation for bilateral irradiation was less than that for single field irradiation. Regarding angular dependence of the RGD, for energies of 13 and 17 keV, the response decreased with increase in the irradiation angle, and the minimum values were 93.5% and 86%, respectively. CONCLUSIONS: Our results showed the dosimetric properties of the RGD, including the energy dependence of the dose response, reproducibly, variation, and angular dependence in low-energy photons and suggest that the accuracy of the absorbed dose in low-energy photons is affected by the readout method and the distribution of radiophotoluminescence centers in the RGD.


Subject(s)
Glass , Luminescent Agents , Photons , Radiometry/methods , Monte Carlo Method
4.
J Radiat Res ; 53(2): 264-71, 2012.
Article in English | MEDLINE | ID: mdl-22510599

ABSTRACT

The frequency distributions of the lineal energy, y, of 160 MeV proton, 150 MeV/u helium, and 490 MeV/u silicon ion beams were measured using a wall-less tissue equivalent proportional counter (TEPC) with a site size of 0.72 µm. The measured frequency distributions of y as well as the dose-mean values, y(D), agree with the corresponding data calculated using the microdosimetric function of the particle and heavy ion transport code system PHITS. The values of y(D) increase in the range of LET below ~10 keV µm(-1) because of discrete energy deposition by delta rays, while the relation is reversed above ~10 keV µm(-1) as the amount of energy escaping via delta rays increases. These results indicate that care should be taken with the difference between y(D) and LET when estimating the ionization density that usually relates to relative biological effectiveness (RBE) of energetic heavy ions.


Subject(s)
Biomimetic Materials , Heavy Ions , Linear Energy Transfer , Radiometry/instrumentation , Radiometry/methods , Equipment Design , Equipment Failure Analysis , Helium , Protons , Reproducibility of Results , Scattering, Radiation , Sensitivity and Specificity , Silicon
5.
Phys Med Biol ; 55(17): 5089-101, 2010 Sep 07.
Article in English | MEDLINE | ID: mdl-20702924

ABSTRACT

The frequency distribution of the lineal energy, y, of a 290 MeV/u carbon beam was measured to obtain the dose-weighted mean of y and compare it with the linear energy transfer (LET). In the experiment, a wall-less tissue-equivalent proportional counter (TEPC) in a cylindrical volume with a simulated diameter of 0.72 microm was used. The measured frequency distribution of y as well as its dose-mean value agrees within 10% uncertainty with the corresponding data from microdosimetric calculations using the PHITS code. The ratio of the measured dose-mean lineal energy to the LET of the 290 MeV/u carbon beam is 0.73, which is much smaller than the corresponding data obtained by a wall TEPC. This result demonstrates that a wall-less TEPC is necessary to precisely measure the dose-mean of y for energetic heavy ion beams.


Subject(s)
Carbon/chemistry , Linear Energy Transfer , Radiometry/instrumentation , Algorithms , Heavy Ions , Models, Biological , Radiometry/methods , Radiotherapy Dosage
7.
Igaku Butsuri ; 20(4): 151-158, 2000.
Article in English | MEDLINE | ID: mdl-12764240

ABSTRACT

Although low energy X-rays have been utilized for mammography, their safety in medical use is a matter of concern. Characteristics of the radiophotoluminescence glass dosimeter, GD-403, consisting of a glass element and filters, were investigated with respect to monochromatic X-rays obtained from a synchrotron radiation for personal monitoring of low energy photons. We focused on low energy X-rays ranging from 8 to 20 keV to study the linearity of the GD-403 response between photon fluence and dose equivalent. The GD-403 was placed on a tough water phantom and irradiated using an 11-15 mm x 0.1-7 mm beam for modulation of the photon fluence. The tough water phantom could be moved through a distance of 110-150 mm with a stepping motor. For the dose equivalent at 1cm depth (H1), 3mm (H3) and 70 &mgr;m (H70), the GD-403 showed sufficient linearities against the photon fluences in the energy regions of 8 to 20 keV, 13 to 20 keV and 13 to 20 keV, respectively. However, H3 and H70 did not provide sufficient linearities in the energy region of 8 to 12 keV. Moreover, we compared the result in this experiment with the value calculated from the absorbed dose of air using the mass absorption coefficient for the X-ray energy ranging from 10 to 20 keV.

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