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1.
J Parasit Dis ; 46(2): 602, 2022 Jun.
Article in English | MEDLINE | ID: mdl-35692464

ABSTRACT

[This corrects the article DOI: 10.1007/s12639-019-01127-1.].

2.
Ann Parasitol ; 67(3): 553-557, 2021.
Article in English | MEDLINE | ID: mdl-34953133

ABSTRACT

Bone cystic echinococcosis is rare disease and its management remain difficult to treat due to frequent recurrences, related to certain locations such as proximal femur and ilium, where radical surgery is difficult to achieve. Medical therapy using Mebendazol can be an ultimate way to insure stabilization and remission of the parasitosis. We present a case of a 37-year-old male who had complaints of pain in left hip and limp four years after surgical management of pertrochanteric fracture of his right lower limb. The first clinical and radiological diagnosis was osteoarthritis of proximal femur and hip. However, higher imaging modalities revealed the diagnosis of hydatid disease of hip with extensive pelvic hydatid cyst localizations. The patient underwent anthelminthic chemotherapy. At 7 years follow-up, the lesions remains stable and the patient has tolerate hip pain, support and walking are impossible without crutches. Hydatid disease of the proximal femur and pelvis must be kept in mind in the differential diagnosis of pathologies of hip-like septic arthritis or tuberculosis. Prolonged medical therapy with anthelmintic medications can constitute an alternative to surgery at very high risk and for extensive lesions where surgery can not achieve carcinologic goals.


Subject(s)
Anthelmintics , Echinococcosis , Echinococcus , Adult , Animals , Anthelmintics/therapeutic use , Echinococcosis/diagnosis , Echinococcosis/drug therapy , Echinococcosis/surgery , Humans , Male , Pelvis , Thigh
3.
J Parasit Dis ; 43(4): 560-565, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31749525

ABSTRACT

Echinococcus granulosus is the etiological agent of cystic echinococcosis (CE), also commonly called hydatidosis. This is a zoonotic infection endemic worldwide, including the Mediterranean basin and Morocco. The genetic variability of Echinococcus granulosus is known to influence development of parasitic cysts in different intermediate hosts, and therefore the epidemiology of infection. Molecular studies have identified nine genotypes of Echinococcus granulosus, eight of them affect humans, grouped today in four distinct species. In Morocco, molecular studies on CE cysts from animals showed the presence, for the large majority of cases, of the G1 genotype (« sheep strain ¼ or Echinococcus granulosus sensu stricto), which is also the cause of the majority of human infections worldwide, and to a lesser extent of the other genotypes (G2 and G3) within Echinococcus granulosus sensu stricto complex. However, so far no genotyping of echinococcal cysts in Morocco has been carried out. We collected CE cysts material from 15 patients diagnosed with abdominal CE in the Meknès-Tafilalt region, Middle Atlas of Morocco, and an endemic area and genotyped by multiplex PCR. The only five cysts from which it was possible to successfully amplify the DNA were all belonging to the G1-G3 genotype, in line with the epidemiology of CE in animals in the same area. Our results add new information, on the human side, to the epidemiological picture of CE in the region, which are important in the context of any control plan for the infection.

4.
Pan Afr Med J ; 20: 127, 2015.
Article in English | MEDLINE | ID: mdl-26097631

ABSTRACT

Trichosporon asahii is a basidiomycete yeast responsible for white piedra and onychomycosis in the immunocompetent host. In the immunocompromised patients, invasive infections are reported; their diagnosis is difficult and they are associated with high mortality rate. Urinary infection due to Trichosporon Asahi is rare but its incidence increasing. We report the case of a 58 year old diabetic patient. The yeast was isolated from urine samples of three consecutive crops in pure form. The patient improved after antifungal therapy.


Subject(s)
Diabetes Mellitus, Type 1/complications , Opportunistic Infections/microbiology , Trichosporon/isolation & purification , Trichosporonosis/microbiology , Urinary Tract Infections/microbiology , Acute Kidney Injury/etiology , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Diabetes Mellitus, Type 1/immunology , Humans , Immunocompromised Host , Male , Middle Aged , Opportunistic Infections/diagnosis , Opportunistic Infections/drug therapy , Trichosporon/classification , Trichosporon/pathogenicity , Trichosporonosis/diagnosis , Trichosporonosis/drug therapy , Urinary Tract Infections/drug therapy , Urine/microbiology , Virulence
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