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5.
Pan Afr Med J ; 25: 30, 2016.
Article in French | MEDLINE | ID: mdl-28154722

ABSTRACT

Granulosa Cell Tumors (GCT) of the ovary are rare tumors belonging to the group of sex cord stromal tumors. They represent 0.6 - 3% of all ovarian tumors and 5% of all malignant tumors. Two different types of GCT can be distinguished: juvenile granulosa cell tumor (JGT) which is characterized by its aggressive potential and adult granulosa cell tumor (AGT) which is the most common and the least aggressive type. GCT of the ovary usually develops recurrences within 5 years of initial diagnosis but they rarely develop local or peritoneal metastases. Although treatment options including surgery with or without chemotherapy or radiation have been reported in treating GCT relapses, there are no standardized protocols for the treatment of relapses. We here present our therapeutic strategy in the treatment of longterm relapses of GCT peritoneal carcinomatosis occurring in two patients 10 years after the initial diagnosis and a review of the literature.


Subject(s)
Granulosa Cell Tumor/pathology , Ovarian Neoplasms/pathology , Peritoneal Neoplasms/secondary , Adult , Female , Granulosa Cell Tumor/diagnosis , Granulosa Cell Tumor/therapy , Humans , Neoplasm Recurrence, Local , Ovarian Neoplasms/diagnosis , Ovarian Neoplasms/therapy , Peritoneal Neoplasms/pathology , Peritoneal Neoplasms/therapy , Time Factors
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