A Report on Cases with Communication Disorders at a Tertiary care Hospital in Mysore District of Karnataka, India: A Retrospective Study Across Five Years.

Communication disorders affect an individual's social, emotional and behavioural well-being. Estimating the number of clients with various causes of communication disorders can assist in the prevention, early identification, intervention, rehabilitation and counselling process. India is the second-largest populated country with diversity in terms of culture and geography. Therefore, estimating the data on number of clients presenting with communication disorders is warranted across different parts of the country. In a retrospective study, the clinical records of cases reporting to the JSS Institute of Speech and Hearing, Mysore, for the last five years were reviewed. A total of 9511 cases diagnosed with communication disorders were included in the study. The percentage of male cases was higher than the females amongst all the types of communication disorders. The percentage of paediatric cases with speech and language disorders was the highest, followed by adult cases. Across the hearing disorders, the highest number of cases were from the adult age group, and the lowest number of hearing-disordered cases were noted in the paediatric age group throughout all five years. Among all the risk factors, perinatal history was the highest seen risk factor, and consanguinity was the lowest seen risk factor associated with communication disorders. The results of the present study revealed that among cases with communication disorders at the tertiary care hospital in Mysore, hearing impairment was one of the most commonly seen conditions, followed by child language disorders. The history of perinatal factors as a risk for communication disorders was noted in a maximum number of cases.

Multiparametric Analysis of Dysphonic Voice - An Evidence from the Discriminant Analysis.

Even though earlier studies have investigated the relationship between various subjective and instrumental measures of voice, determining a standardized set of voice parameters in evaluating dysphonic voices can help in better diagnostic distinctions and judgment of the treatment outcomes in voice disorders. Thus, the primary objective was to examine the differences in the objective and subjective measures of voice between the participants with dysphonia and participants with a clinically normal voice. The subsequent objective was to identify the group of parameters sensitive to vocal changes in dysphonia using discriminant analysis. Two groups of participants were included in the study. Group 1 comprised of 15 participants with dysphonia. Group 2 included 15 participants with a clinically normal voice. Sustained phonations of vowels were recorded from the participants of both groups and were analyzed perceptually using the GRBAS rating scale. Acoustic, cepstral, spectral, and electroglottographic measures were analyzed from dysphonic voices and normal controls. There were significant differences in both instrumental and perceptual measures between the participants with and without dysphonia. The set of five parameters that were significant predictors that discriminated the dysphonic voice from the clinically normal voice with 100% accuracy was also determined using discriminant analysis. Future investigations on the relation between the specific instrumental and perceptual measures of voice identified in the present study among individuals with various voice disorders can deliver more promising and comprehendible insights into better diagnostic distinctions of voice disorders.

Cross-cultural Adaptation and Validation of the Vocal Performance Questionnaire into Kannada.

BACKGROUND/OBJECTIVES: Vocal Performance Questionnaire (VPQ) is a short and convenient tool with one-dimensional consistency to evaluate the vocal performance. Developing the Kannada version of VPQ can be a useful self-assessment clinical tool for evaluating dysphonia symptoms in Kannada-speaking patients. Hence, the objective of the study was to translate the VPQ into Kannada and to evaluate the psychometric properties and the cutoff scores for the Kannada version of the VPQ (VPQ-K). STUDY DESIGN: This investigation deployed a non-randomised, prospective standard group comparison. METHODS: VPQ was translated to Kannada and administered to 71 participants (37 males and 34 females) diagnosed with voice disorder with a mean age of 43.94 ± 15.31 years and 71 age and gender-matched participants with a clinically normal voice. RESULTS: The test-retest reliability of the VPQ-K was measured through Intra class correlation, and the results indicated excellent test-retest reliability. The Internal consistency of VPQ-K was determined using the Split half reliability by calculating the Spearmen-Brown coefficient, and the results revealed that VPQ-K had very strong internal consistency. Results also indicated that the participants in the control group had significantly lower VPQ-K scores compared to the participants in the study groups, indicating that VPQ-K had good construct validity. Receiver Operating Characteristic (ROC) curve analysis showed a cutoff point of 18.50 for VPQ-K. CONCLUSIONS: As VPQ-K is a quick, easy to fill and low-burden self-assessment tool, VPQ-K can be proposed as a sensitive clinical tool to assess the vocal performance in Kannada-speaking patients with voice disorders and to evaluate the treatment outcome.

Adaptation and Validation of the Voice-Related Quality of Life Measure into Kannada.

BACKGROUND: Earlier researchers have developed various objective tools to document the impact of dysphonia on the patient's daily living and quality of life. Of all these available tools, Voice Related Quality of Life (V-RQOL) is one of the essential self-reported tools to document the quality of life related to voice. Thus, developing the Kannada version of V-RQOL can be a useful tool in the clinical assessment of Kannada-speaking dysphonic patients. OBJECTIVES: To translate the V-RQOL into Kannada and to evaluate the psychometric properties and the cut off scores for the Kannada version of the V-RQOL. STUDY DESIGN: This investigation deployed a non-randomized, prospective standard group comparison. METHODS: V-RQOL was translated to Kannada and was administered to 70 patients with voice disorders (42 males and 28 females) with a mean age of 43.2 ± 15.8 years, and 70 age and gender-matched participants with a clinically normal voice. RESULTS: Spearman's correlation coefficient was more than 0.94 indicating a good test-retest reliability. Therefore, the Kannada version of VRQOL had a good level of reproducibility. The test also showed a Cronbach alpha coefficient of 0.92, indicating a strong internal consistency of the Kannada version of VRQOL. Receiver Operating Characteristic (ROC) curve analysis revealed that the cut off score for the Kannada version of VRQOL was 93.75 indicating that Kannada version of VRQOL had an excellent construct validity. CONCLUSION: The present study findings revealed that the Kannada version of VRQOL is a reliable, valid and sensitive self-assessment tool to document the impact of voice problems on the patient's quality of life.

Multiparameter Voice Assessment in Dysphonics: Correlation Between Objective and Perceptual Parameters.

BACKGROUND: Perceptual assessment and objective measures of voice provide a quantifiable tool for determining the degree of glottal closure, thus helping to distinguish dysphonic voices from normal voices. The correlation between the perceptual and objective parameters of voice in dysphonic can enable the voice pathologist to be more effective in differentiating the normal voices from dysphonic voices. However, only a few studies have investigated the correlation between these measures. OBJECTIVE: To document the differences in the perceptual and objective parameters of voice in participants with dysphonia and normal controls and to investigate the correlation between the perceptual and objective parameters of voice among participants with dysphonia. STUDY DESIGN: This investigation deployed standard group comparison and a retrospective study. METHODS: Two groups of participants were included in the study. Participants in group 1 were diagnosed as having a voice disorder secondary to organic pathologies and group 2 participants had a clinically normal voice. Phonation samples of all the participants were collected and perceptual analysis was carried out using the GRBAS rating scale. As part of the objective measures, acoustic and cepstral measures were extracted from the phonation samples. RESULTS: The analysis of the results revealed significant differences in perceptual ratings between the normal (control) and dysphonic groups. The mean values of all the objective measures of voice presented significant differences between participants of both groups. The perceptual ratings of grade, breathiness, and roughness showed better correlations with the cepstral measures than with the time-based acoustic measures. CONCLUSIONS: Further foraging research on the correlation between perceptual and objective measures of voice in various degrees of dysphonia will improve reliability while discriminating and quantifying hoarse, harsh and breathy voices from modal voices.

Multiparametric analysis of voice following prolonged voice use and voice rest in teachers: evidence from discriminant analysis.

PURPOSE: Even though recent investigations have used multiparametric protocol, the set of robust parameters in determining the effects of vocal fatigue and voice rest in teachers is not clear. The first objective of the study was to document the impact of prolonged voice use and voice rest on the subjective and objective voice parameters among Indian secondary school teachers. The second objective was to determine the set voice parameters sensitive to vocal changes resulting from continuous voice use and voice rest. METHOD: The study included 15 male and 15 female secondary school teachers with a clinically normal voice and no history of voice disorders. Phonation samples were recorded in three different conditions, i.e., condition 1 (before voice use), condition 2 (following voice use), and condition 3 (following voice rest). The vocal Fatigue Index (version 2) was administered before the voice recordings in all three conditions. The objective parameters, namely fundamental frequency, range of fundamental frequency, jitter (%), shimmer (%), harmonic to noise ratio, and smoothened cepstral peak prominence, were extracted. RESULTS: Results revealed that fundamental frequency, jitter, shimmer, Harmonic to noise ratio, and smoothened cepstral peak prominence were significantly different across the three conditions. The discriminant analysis revealed that only three parameters classified 98.3% of samples accurately between the three conditions. CONCLUSION: Further research on the correlation between the other subjective and the objective parameters of voice after vocal fatigue would provide more penetrating and ample in-depth insights into the assessment and quantification of vocal fatigue.

A novel technique to monitor thermal discharges using thermal infrared imaging.

Coastal temperature is an important indicator of water quality, particularly in regions where delicate ecosystems sensitive to water temperature are present. Remote sensing methods are highly reliable for assessing the thermal dispersion. The plume dispersion from the thermal outfall of the nuclear power plant at Kalpakkam, on the southeast coast of India, was investigated from March to December 2011 using thermal infrared images along with field measurements. The absolute temperature as provided by the thermal infrared (TIR) images is used in the Arc GIS environment for generating a spatial pattern of the plume movement. Good correlation of the temperature measured by the TIR camera with the field data (r(2) = 0.89) make it a reliable method for the thermal monitoring of the power plant effluents. The study portrays that the remote sensing technique provides an effective means of monitoring the thermal distribution pattern in coastal waters.

Dissolution of synthetic uranium dibutyl phosphate deposits in oxidizing and reducing chemical formulations.

Permanganate and nitrilotriacetic acid (NTA) based dilute chemical formulations were evaluated for the dissolution of uranium dibutyl phosphate (U-DBP), a compound that deposits over the surfaces of nuclear reprocessing plants and waste storage tanks. A combination of an acidic, oxidizing treatment (nitric acid with permanganate) followed by reducing treatment (NTA based formulation) efficiently dissolved the U-DBP deposits. The dissolution isotherm of U-DBP in its as precipitated form followed a logarithmic fit. The same chemical treatment was also effective in dissolving U-DBP coated on the surface of 304-stainless steel, while resulting in minimal corrosion of the stainless steel substrate material. Investigation of uranium recovery from the resulting decontamination solutions by ion exchange with a bed of mixed anion and cation resins showed quantitative removal of uranium.

Immobilization of Cr(VI) and its reduction to Cr(III) phosphate by granular biofilms comprising a mixture of microbes.

We assessed the potential of mixed microbial consortia, in the form of granular biofilms, to reduce chromate and remove it from synthetic minimal medium. In batch experiments, acetate-fed granular biofilms incubated aerobically reduced 0.2 mM Cr(VI) from a minimal medium at 0.15 mM day(-1) g(-1), with reduction of 0.17 mM day(-1) g(-1) under anaerobic conditions. There was negligible removal of Cr(VI) (i) without granular biofilms, (ii) with lyophilized granular biofilms, and (iii) with granules in the absence of an electron donor. Analyses by X-ray absorption near edge spectroscopy (XANES) of the granular biofilms revealed the conversion of soluble Cr(VI) to Cr(III). Extended X-ray absorption fine-structure (EXAFS) analysis of the Cr-laden granular biofilms demonstrated similarity to Cr(III) phosphate, indicating that Cr(III) was immobilized with phosphate on the biomass subsequent to microbial reduction. The sustained reduction of Cr(VI) by granular biofilms was confirmed in fed-batch experiments. Our study demonstrates the promise of granular-biofilm-based systems in treating Cr(VI)-containing effluents and wastewater.

Effect of reactive atmosphere of synthesis on properties of nano-ceria.

Ceria is an important rare-earth oxide with ever increasing applications. In nanocrystalline form, ceria exhibits novel and improved properties compared to its microcrystalline counterpart. The variation in the properties was observed to be a function of lowering particle size. This was also attributable to the presence and extent of Ce in 3+ state in ceria. Thermal decomposition of a thermally less stable cerium metal salt is an useful and simple method for the synthesis of nanocrystalline ceria. As atmosphere under which the decomposition occurs is expected to alter the Ce3+ content and thus the property, the present study is to investigate the effect of reactive atmosphere of decomposition vis-à-vis the particle size on the property of nanocrystalline ceria. Nanocrystalline ceria was synthesized by controlled thermal decomposition of cerium nitrate under four different atmospheres and the products were analyzed by X-Ray Diffraction, X-ray photoelectron spectroscopy and Laser Raman Spectroscopy. The observed property variation was found to be more dependent on the Ce3+ content thus the synthesis atmosphere rather than the particle size.

Biofouling and microbial corrosion problem in the thermo-fluid heat exchanger and cooling water system of a nuclear test reactor.

This article discusses aspects of biofouling and corrosion in the thermo-fluid heat exchanger (TFHX) and in the cooling water system of a nuclear test reactor. During inspection, it was observed that >90% of the TFHX tube bundle was clogged with thick fouling deposits. Both X-ray diffraction and Mossbauer analyses of the fouling deposit demonstrated iron corrosion products. The exterior of the tubercle showed the presence of a calcium and magnesium carbonate mixture along with iron oxides. Raman spectroscopy analysis confirmed the presence of calcium carbonate scale in the calcite phase. The interior of the tubercle contained significant iron sulphide, magnetite and iron-oxy-hydroxide. A microbiological assay showed a considerable population of iron oxidizing bacteria and sulphate reducing bacteria (10(5) to 10(6) cfu g(-1) of deposit). As the temperature of the TFHX is in the range of 45-50 degrees C, the microbiota isolated/assayed from the fouling deposit are designated as thermo-tolerant bacteria. The mean corrosion rate of the CS coupons exposed online was approximately 2.0 mpy and the microbial counts of various corrosion causing bacteria were in the range 10(3) to 10(5) cfu ml(-1) in the cooling water and 10(6) to 10(8) cfu ml(-1) in the biofilm.

Spectroscopic characterization of nanocrystalline chromium nitride (CrN).

Nanocrystalline chromiuim nitride has been synthesised by direct gas phase nitridation of nanocrystalline chromia at 1100 degrees C in ammonia-atmosphere. XRD of this material showed formation of single phase CrN with particle size around 20 nm. AFM studies showed particle distribution along with some soft agglomerated nanostructures. Nanocrystalline Cr2O3 and partially-as well as fully--converted nanocrystalline CrN were also investigated using various spectroscopic techniques like XPS, FT-IR, and Raman for gaining insight into the conversion pathways. Spectroscopic investigations of these materials clearly indicate that complete conversion of CrN occurs by nitriding at 1100 degrees C for 4 hrs. The salient spectroscopic features of these nanocrystalline materials with respect to their microcrystalline counterparts are discussed.

Biodegradation of nitrilotriacetic acid (NTA) and ferric-NTA complex by aerobic microbial granules.

Development of mixed-culture microbial granules under aerobic conditions in a sequencing batch reactor (SBR), capable of completely degrading a recalcitrant metal chelating agent is reported. In laboratory-scale reactor studies, the microbial granules degraded 2mM of free nitrilotriacetic acid (NTA) and Fe(III)-NTA completely in 14 and 40 h, respectively. Free NTA was degraded at a specific rate of 0.7 mM (gMLSS)(-1)h(-1), while Fe(III)-NTA was degraded at a specific rate of 0.37 mM (gMLSS)(-1)h(-1). Achievement of significant degradation rates of NTA and ferric-NTA in double-distilled water suggests that the microbial metabolism is not constrained by lack of essential elements. Efficient degradation of recalcitrant synthetic chelating agents by aerobic microbial granules suggests their potential application in a variety of situations where heavy metals or radionuclides are to be co-disposed with metal chelating agents.

Optical absorption and photoluminescence spectroscopy of the growth of silver nanoparticles.

Results obtained from the optical absorption and photoluminescence (PL) spectroscopy experiments have shown the formation of excitons in the silver-exchanged glass samples. These findings are reported here for the first time. Further, we investigate the dramatic changes in the photoemission properties of the silver-exchanged glass samples as a function of postannealing temperature. Observed changes are thought to be due to the structural rearrangements of silver and oxygen bonding during the heat treatments of the glass matrix. In fact, photoelectron spectroscopy does reveal these chemical transformations of silver-exchanged soda glass samples caused by the thermal effects of annealing in a high vacuum atmosphere. An important correlation between temperature-induced changes of the PL intensity and thermal growth of the silver nanoparticles has been established in this Letter through precise spectroscopic studies.

Spectrophotometric method for determination parts per million levels of cyclohexylamine in water.

UV-vis spectrophotometric method for the analysis of cyclohexylamine (CHA) in aqueous medium in the range of 0.3-20 ppm was developed by coupling CHA with sodium 1,2-naphthaquinone-4-sulphonate (NQS). At 470 nm a calibration slope of 0.028 OD ppm(-1) was observed. Minimum detection limit was 0.3 ppm with standard deviation of 0.1 ppm. Reagent concentration and solution pH for the analysis are optimised by studying its effect on absorbance at 470 nm. The method was applied to analyse CHA for evaluating the performance of ion exchange resin used in condensate purification plant (CPP) of power station where, CHA is used as all volatile treatment (AVT) reagent to inhibit steam generator (SG) corrosion. Structure of the adduct formed by coupling CHA with NQS is elucidated using NMR ((1)H and (13)C) and IR spectra, CHN analysis and mole ratio variation method.

Software simulation of the EEG.

The literature contains many examples of digital procedures for the analytical treatment of electroencephalograms, but there is as yet no standard by which those techniques may be judged or compared. This paper proposes one method of generating an EEG, based on a computer program for Zetterberg's simulation. It is assumed that the statistical properties of an EEG may be represented by stationary processes having rational transfer functions and achieved by a system of software filters and random number generators. The model represents neither the neurological mechanism response for generating the EEG, nor any particular type of EEG record; transient phenomena such as spikes, sharp waves and alpha bursts also are excluded. The basis of the program is a valid 'partial' statistical description of the EEG; that description is then used to produce a digital representation of a signal which, if plotted sequentially, might or might not by chance resemble an EEG, that is unimportant. What is important is that the statistical properties of the series remain those of a real EEG; it is in this sense that the output is a simulation of the EEG. There is considerable flexibility in the form of the output, i.e. its alpha, beta and delta content, which may be selected by the user, the same selected parameters always producing the same statistical output. The filtered outputs from the random number sequences may be scaled to provide realistic power distributions in the accepted EEG frequency bands and then summed to create a digital output signal, the 'stationary EEG'.(ABSTRACT TRUNCATED AT 250 WORDS)