Oral Propranolol Therapy for Infantile Hemangioma: Long-term Follow-up.

ß-blocker therapy is currently the treatment of choice for infantile hemangiomas (IH), albeit with limited data on long-term treatment outcomes. Herein, authors treated 67 IH lesions in 47 patients with oral propranolol at 2 mg/kg/d for a median of 9 mo and followed them up for a median of 48 mo. While no maintenance therapy was required for 18 lesions (26.9%), the rest needed maintenance therapy. Both treatment regimens had comparable efficacy (83.3±23.9% and 92.0±13.8%) but chances of IH recurrence was higher in lesions requiring maintenance therapy. Also, patients treated at ≤5 mo of age had a significantly better response and a lower recurrence rate than patients treated at >5 mo of age (95.0±7.9% vs. 87.0±17.5%, p = 0.05). Authors' experience suggests that longer durations of maintenance therapy offered no added advantage to the overall improvement of IH while treatment initiation at an earlier age showed better improvement and lower recurrence rates.

Forecasting in humanitarian operations: Literature review and research needs.

Forecasting research in the humanitarian context is scarce. In this literature review, our goal is not only to show why forecasting research is important for the humanitarian sector, but also to identify what has been done so far, and where are the needs for further research. We conducted a structured literature search in Scopus, Web of Science, ABI Inform, and Google Scholar resulted in only 38 papers published between 1990 and 2018. Based on our findings we highlight three case studies as exemplary research in forecasting within the humanitarian context and list seven future research streams with specific research needs identified in each stream.

Ambidextrous humanitarian organizations.

The COVID-19 pandemic disrupted life as usual around the globe. Efforts to control the spread of the virus with lockdowns and border closures pushed millions of people into food and social insecurity. Most research on humanitarian organizations have been dominated by the uncertainty and urgency of disaster response operations. However, some humanitarian organizations also operate in long-term continuous aid programs where efficiency is the key goal. We analyzed the operations of food banks in the Feeding America network and The Salvation Army USA, and found them to be ambidextrous organizations. The ambidextrous humanitarian organizations like food banks and Salvation Army, focus on long-term continuous aid programs, specifically pertaining to the sustenance of the communities they serve, but also play a key part as first responders or as local agencies aiding in disaster relief and response. We propose a framework to analyze disaster, development, and sustenance aid supply chains, and identify future research opportunities.

Pemphigoid gestationis: a rare pregnancy dermatosis treated with a combination of IVIg and rituximab.

Pemphigoid gestationis is a rare autoimmune subepidermal bullous dermatosis occurring during pregnancy and post partum. A 32-year-old woman developed itchy urticarial wheals over the trunk and extremities at 6 months of gestation. This was not controlled with antihistamines, and 2 months later, the patient developed multiple vesiculobullous lesions. The patient had an exacerbation 3 weeks post-delivery. She did not go into remission for 6 months post partum despite treatment with prednisolone 40 mg/day, doxycycline 100 mg two times per day and dapsone 100 mg/day. The patient went into remission following treatment with three courses of intravenous immunoglobulin 2 mg/kg/course and 2 doses of rituximab 1 g at a 2-week interval.