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1.
J Pharm Bioallied Sci ; 13(Suppl 1): S367-S369, 2021 Jun.
Article in English | MEDLINE | ID: mdl-34447111

ABSTRACT

BACKGROUND: The present study determined the effect of implant angulation and implant number on the dimensional precision of implant definitive casts. MATERIALS AND METHODS: Three definitive casts with implant analogs placed in a triangular pattern were made from dental stone. Group I was control group, Group II in which implant numbers 1 and 3 were at 5° convergence to the implant number 2. Group III in which implant numbers 1 and 3 are at 5° divergence to the implant number 2. Group IV in which implant numbers 1 and 3 are at 10° convergence to the implant number 2. Implant analogs were secured in all the definitive casts with cyanoacrylate. Three open tray impressions of the definitive cast were obtained and poured in Type IV dental stone. Coordinates in the three planes were measured at implant analog top surface and base of the cast using a fine tip measuring stylus. The data were aligned and angular differences between implant analog vectors from definitive and duplicate casts were measured. RESULTS: There was a significant correlation between dental implant number and dental implant angulation (P < 0.05). There was a significant result when comparing the effect of the parallel group from 5° divergence and 10° convergence groups. A significant results while comparing the parallel group with 5° divergence and 10° convergence was obtained whereas while comparing 5° divergence, 5° divergence, and 10° convergence a nonsignificant difference was obtained (P > 0.05). CONCLUSION: Close proximity of implant angulation toward right-angled direction results in higher precision of implant.

2.
J Contemp Dent Pract ; 21(1): 83-90, 2020 Jan 01.
Article in English | MEDLINE | ID: mdl-32381807

ABSTRACT

AIM: To study the efficacy of topical curcumin mucoadhesive semisolid gel, triamcinolone acetonide/hyaluronidase mucoadhesive semisolid gel, and a combination of both in the treatment of oral submucous fibrosis (OSMF). MATERIALS AND METHODS: One hundred and twenty patients diagnosed with OSMF were randomly divided into groups I, II, and III. Each patients in groups I, II, and III was given professionally prepared mucoadhesive semisolid gel of curcumin, a combination of triamcinolone acetonide and hyaluronidase mucoadhesive semisolid gel, and a combination of all three, respectively. Patients were instructed to apply the gel thrice daily for 6 weeks on buccal mucosa bilaterally using the tip of index finger. Three parameters were evaluated at the end of each week, namely, mouth opening, burning on visual analog scale (VAS), and the color of oral mucosa on the binary scale. The results were subjected to statistical analysis. RESULTS: It was observed that the group administered the three drug combinations achieved the greatest mouth opening (mean increase 4.05 mm) as compared to the other two groups. It was observed that triamcinolone and hyaluronidase group reported reduction in burning sensation on VAS (mean difference 6) as compared to the other two groups. It was observed that group III (1% curcumin, 1% hyaluronidase and 0.1% triamcinolone acetonide combined) drug therapy showed better change in mucosa color as compared to groups I (1% curcumin) and II. CONCLUSION: Thus, we can conclude that curcumin has a therapeutic effect on patients diagnosed with OSMF. Maximum utilization and enhanced drug delivery were achieved with the help of a combination other two active drugs, namely, triamcinolone and hyaluronidase. CLINICAL SIGNIFICANCE: Curcumin role in the treatment of oral cancers and the precancer lesion is very promising.


Subject(s)
Curcumin , Oral Submucous Fibrosis , Humans , Hyaluronoglucosaminidase , Mouth Mucosa , Triamcinolone Acetonide
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