ABSTRACT
The aim of this study was to investigate an outbreak of enterovirus infection in Lithuania in 2001, as well as the clinical presentation and outcome of the disease. Thirty children aged 1 month to 15 years were referred to hospital with suspected enterovirus infection during the period August-October 2001. Echovirus 13 (EV-13) was isolated from eight (26.7%) cases. No other pathogens were detected. Infection presented predominantly as viral meningitis, and rarely as a febrile illness with rash. The outcome was good for all patients. This is the first report of EV-13 from Lithuania.
Subject(s)
Disease Outbreaks , Echovirus Infections/epidemiology , Enterovirus B, Human/isolation & purification , Meningitis, Viral/epidemiology , Adolescent , Child , Child, Preschool , Echovirus Infections/virology , Female , Fever/virology , Humans , Infant , Lithuania/epidemiology , Male , Meningitis, Viral/virologyABSTRACT
AIM: To determine the prevalence of lactose malabsorption in young Lithuanian atopic dermatitis children; to evaluate the relationship between lactose malabsorption and the duration of exclusive breastfeeding, and the relationship between lactose malabsorption and cow's milk intolerance in parents and grandparents. METHODS: 144 children with atopic dermatitis aged 1.5-24 mo (study group) and 32 children without symptoms of allergic diseases aged 1.5-23 mo (control group) were investigated. Lactose and glucose-galactose absorption tests based on serial blood glucose determination, culture of stool, latex agglutination test for rotavirus and microscopic examination of stool for parasites were performed. RESULTS: Lactose malabsorption was determined in 59 (40.9%) and glucose-galactose malabsorption in 17 (11.8%) children with atopic dermatitis. The risk of developing lactose malabsorption was higher in children fed exclusively on breast milk up to 1 mo of age than in children fed exclusively on breast milk for 4 to 6 mo (OR: 2.62; 95% CI: 1.02-6.75). Lactose malabsorption was significantly more frequent in patients whose mothers did not tolerate cow's milk (20/30; 66.7%) than in patients whose mothers were tolerant to it (39/95; 41.1%) (p = 0.02). CONCLUSION: Lactose malabsorption was determined in 40.9% of Lithuanian atopic dermatitis children aged under 2 y. Lactose malabsorption appeared to be associated with the duration of exclusive breastfeeding up to only 1 mo and mothers' milk intolerance.
