Subject(s)
Cardiac Pacing, Artificial , Electrocardiography , Heart Rate , Tachycardia, Ventricular/diagnosis , Action Potentials , Aged , Catheter Ablation , Defibrillators, Implantable , Electric Countershock , Humans , Male , Predictive Value of Tests , Recurrence , Tachycardia, Ventricular/physiopathology , Tachycardia, Ventricular/therapy , Time Factors , Treatment OutcomeABSTRACT
Aims: Multipoint pacing (MPP) permits simultaneous multisite pacing of the left ventricle (LV); initial studies suggest haemodynamic and clinical benefits over conventional (single LV site) cardiac resynchronization therapy (CRT). The aim of this study was to estimate the impact of MPP activation on battery longevity in routine clinical practice. Methods and results: Patient (n = 46) and device data were collected from two centres at least 3 months after MPP-CRT device implantation. Multipoint pacing programming was based on the maximal possible anatomical LV1/LV2 separation according to three predefined LV pacing capture threshold (PCT) cut-offs (≤1.5 V; ≤4.0 V; and ≤6.5 V). Estimated battery longevity was calculated using the programmed lower rate limit, lead impedances, outputs, and pacing percentages. Relative to the longevity for conventional CRT using the lowest PCT (8.9 ± 1.2 years), MPP activation significantly shortened battery longevity for all three PCT cut-offs (≤1.5 V, -5.6%; ≤4.0 V, -16.9%; ≤6.5 V, -21.3%; P's <0.001). When compared with conventional CRT based on longest right ventricle-LV delay (8.3 ± 1.3 years), battery longevity was significantly shortened for the MPP ≤ 4.0 V and ≤6.5 V cut-offs (-10.8 and -15.7%, respectively; P's <0.001). Maximal LV1/LV2 spacing was possible in 23.9% (≤1.5 V), 56.5% (≤4.0 V), and 69.6% (≤6.5 V) of patients. Conclusion: Multipoint pacing activation significantly reduces battery longevity compared with that for conventional CRT configuration. When reasonable MPP LV vector PCTs (≤4.0 V) are achieved, the decrease in battery longevity is relatively small which may prompt the clinician to activate MPP.
Subject(s)
Cardiac Resynchronization Therapy Devices , Cardiac Resynchronization Therapy/methods , Electric Power Supplies , Heart Failure/therapy , Ventricular Function, Left , Aged , Cardiac Resynchronization Therapy/adverse effects , Cross-Sectional Studies , Equipment Failure , Female , Heart Failure/diagnosis , Heart Failure/physiopathology , Humans , Male , Middle Aged , Prospective Studies , Spain , Time Factors , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Catheter Ablation/methods , Ventricular Premature Complexes/therapy , Myocardial Ischemia/complications , Risk Factors , Treatment OutcomeABSTRACT
No disponible
