ABSTRACT
Aim of the study was to investigate prevalence and special characteristics of manifestations of painless myocardial ischemia (PMI) in patients with chronic obstructive pulmonary disease (COPD) at exacerbation stage with various degree of severity and to assess risk of cardiovascular events in this group of patients. We carried out complex clinical-instrumental and laboratory examination of 54 patients with COPD. Examination included 24 hour Holter ECG monitoring, registration of parameters of pulmonary function, and endothelium dependent and independent vasoreactivity, determination of lipid spectrum, blood gases composition. We established that aggravation of degree of COPD severity was associated with increase of frequency of episodes of PMI and their total daily duration. During 12 months follow up incidence of cardiovascular events in the group of patients with episodes of PIM was 66.6%
Subject(s)
Asymptomatic Diseases/epidemiology , Myocardial Ischemia , Pulmonary Disease, Chronic Obstructive/complications , Electrocardiography, Ambulatory/methods , Follow-Up Studies , Humans , Incidence , Male , Middle Aged , Myocardial Ischemia/diagnosis , Myocardial Ischemia/epidemiology , Myocardial Ischemia/etiology , Myocardial Ischemia/physiopathology , Pulmonary Disease, Chronic Obstructive/physiopathology , Respiratory Function Tests/methods , Risk Assessment , Risk Factors , Severity of Illness IndexABSTRACT
The hospital-based rehabilitative treatment was given to 36 patients presenting with combined cardiopulmonary pathology. It included electrophoresis of the the salt sediment from Amurskaya-2 mineral water and the assessment of its efficacy in clinical, functional, and laboratory studies. It was shown that this therapeutic modality had positive influence on lipid metabolism and improved the functional state of myocardium. Overall, the rehabilitative potential of the treatment increased.
