Phase-shift-controlled logic gates in Y-shaped nonlinearly coupled chains.

We introduce a model system composed of two input discrete chains nonlinearly coupled to a single output chain which mimics the geometry of Y-shaped carbon nanotubes, photonic crystal wave guides, and DNA junctions. We explore the capability of the proposed system to perform logic gate operations based on the transmission of phase-shifted harmonic incoming waves. Within a tight-binding approach, we determine the exact transmission spectrum which exhibits a nonlinear induced bistability. Using a digitalization scheme of the output signal based on amplitude modulation, we show that AND, OR, and XOR logic operations can be achieved. Nonlinearity strongly favors the realization of logic operations in the regime of large wavelengths, while phase shifting is required for the OR logic gate to be realizable. A detailed analysis of the contrast ratio shows that optimal operation of the AND and OR logic gates takes place when the nonlinear response is the predominant physical property distinguishing the coupling and regular sites. These results point towards the possibility of Y-branched junctions to perform logic operations based on the transmission of traveling waves.

Effects of the concentration and composition of in-office bleaching gels on hydrogen peroxide penetration into the pulp chamber.

UNLABELLED: In tooth whitening, the hydrogen peroxide (HP) diffuses in the enamel and dentin, reaching the pulp. This in vitro study aimed to quantify the penetration of HP in the pulp chamber in teeth submitted to bleaching agents of different concentrations of HP without calcium (HP 20% [20CF], HP 35% [35CF]) and with calcium (HP 20% [20CC], HP 35% [35CC]). METHOD: Fifty human premolars were sectioned 3 mm from the cemento-enamel junction and the pulp tissue was removed. The teeth were divided into five groups according to treatment and with a control group (n=10). An acetate buffer solution was placed in the pulp chamber of all teeth. The control group was exposed only to distilled water, while the other groups were treated with a bleaching procedure, according to the manufacturer's recommendations. After treatment, the acetate buffer solution was transferred to a glass tube in which leuco-crystal violet and peroxidase solutions were added, resulting in a blue solution. The optical density of this blue solution was determined spectrophotometrically and converted into micrograms equivalent to the HP. Data were analyzed using analysis of variance and Tukey tests (α=0.05). RESULTS: The HP concentration did not affect the HP inside the pulp chamber, but the presence of calcium significantly reduced it (p<0.0001). CONCLUSION: The amount of HP that reaches the pulp chamber depends on the bleaching protocol and the product employed, and it seems to be less affected by HP concentration.

Nonreciprocal transmission through a saturable nonlinear asymmetric dimer.

We investigate the nonreciprocal diodelike behavior of a dimer with an asymmetric on-site potential and a saturable nonlinearity. The dimer is coupled to linear side chains. The spectra of transmission and the rectifying factor are analytically obtained using a backward iteration of the set of discrete nonlinear Schrödinger equations used to model the wave propagation through the nonlinear dimer. We show that the windows of bistable behavior leading to a pronounced nonreciprocal diodelike transmission become wider and displaced to higher input field intensities as the saturation coefficient increases. Further, saturation of the nonlinear response has opposite impacts on the rectifying action over short- and long-wavelength input signals within the second bistability window. In the first window, the rectifying action is not compromised by the saturation, thus showing that a weak contribution of high-order susceptibilities to the nonlinear response can improve the efficiency of the nonreciprocal transmission. The rectifying action of a dimer with an asymmetric nonlinearity is also discussed.

Geometrical and Anderson transitions in harmonic chains with constrained long-range couplings.

Low-dimensional systems with long-range couplings usually present phase transitions which are absent in the short-ranged counterpart model. In this work, we show that a harmonic chain with long-range couplings restricted by a cost function proportional to the chain length N exhibits two distinct phase transitions. In the present model, two sites at a distance r>1 are connected by a spring with probability 1/r(α) with the constraint that the total length of the non-nearest-neighbor couplings is limited to λN, where λ is a cost parameter. A geometrical phase transition is found at α=1.5 between a phase with a finite number of long-range couplings and a phase on which the number of long-range couplings is proportional to the system size. Further, the normal vibrational modes of this chain display a phase transition from delocalized to localized modes at a smaller value of α. Maximum effective disorder is reached at α=2 for which the frequency of the lowest vibrational mode exhibits a pronounced peak.

Prevalence, serologic and genetic studies of high expressers of the blood group A antigen on platelets*.

OBJECTIVE/AIM: The aim of this study is to describe the distribution of the platelet blood group A antigenicity in Euro-Brazilians (EUBs) and Afro-Brazilians (AFBs). BACKGROUND: A small but significant proportion of individuals express high levels of A or B antigen on their platelets corresponding to the erythrocyte ABO group. The mechanism of increased antigen expression has not been elucidated. MATERIAL/METHODS: A cohort of 241 blood group A donors was analysed by flow cytometry. Although mean fluorescence intensity (MFI) is a typical continuous variable, platelets were screened and divided into two categories: low expressers (LEs) and high expressers (HEs). A three-generation family was investigated looking for an inheritance mechanism. RESULTS: The prevalence of the HE platelet phenotype among group A(1) donors was 2%. The mean of MFI on platelets of A(1) subgroup of EUBs differs from that of AFBs (P = 0·0115), whereas the frequency of the HE phenotype was similar between them (P = 0·5251). A significant difference was found between sexes (P = 0·0039). Whereas the serum glycosyltransferase from HE family members converted significantly more H antigen on group O erythrocytes into A antigens compared with that in LE serum, their ABO, FUT1 and FUT2 genes were consensus. The theoretically favourable, transcriptionally four-repeat ABO enhancer was not observed. CONCLUSION: The occurrence of HE in several members suggests familial aggregation. Indeed, in repeated measures, stability of the MFI values is suggesting an inherited condition. Factors outside the ABO locus might be responsible for the HE phenotype. Whether the real mechanism of inheritance is either of a polygenic or of a discrete Mendelian nature remains to be elucidated.

Tunable reflectance spectra of multilayered cholesteric photonic structures with anisotropic defect layers.

In this paper, we investigate the spectral characteristics of normal incident light reflected by a multilayered structure composed of an alternated sequence of single-pitch cholesteric liquid-crystal (ChLC) and anisotropic layers. Using the Berreman 4x4 matrix formalism, we numerically obtain the reflection spectrum and the chromaticity diagram as a function of the anisotropic layers thickness d. For d-->0 , the structure behaves like a single ChLC layer, showing a single reflection band. As the anisotropic layer thickness increases, the reflection band shifts toward high-wavelength spectral regions, while new reflection bands appear. As a consequence, the reflection chromaticity continuously changes with d . It is observed that a suitable choice of the anisotropic layer thickness can produce a threefold reflection band with a red-green-blue associated color for both polarized and unpolarized incident lights.

Finite-size scaling and disorder effect on the transmissivity of multilayered structures with metamaterials.

We investigate the influence of metamaterials on the scaling laws of the transmission on multilayered structures composed of random sequences of ordinary dielectric and metamaterial layers. The spectrally averaged transmission in a frequency range around the fully transparent resonant mode is shown to decay with the total number of layers as 1/N. Such thickness dependence is faster than the 1/N(1/2) decay recently reported to take place in random sequences of ordinary dielectric slabs. The interplay of strong localization and the emergence of resonant modes within the gap leads to a non-monotonous disorder dependence of the transmission that reaches a minimum at an intermediate disorder strength.

Chagas disease in an area of recent occupation in Cochabamba, Bolivia.

INTRODUCTION: A descriptive, entomological and seroepidemiological study on Chagas disease was conducted in a place of recent occupation on the outskirts of Cochabamba, Bolivia: Avaroa/Primer de Mayo (population:3,000), where the socio-economic level is low and no control measures have been made available. METHODS: The immunofluorescent antibody test (IFAT) was used for IgG and IgM anti-Trypanosoma cruzi antibodies in filter paper bloodspot eluates from 128 subjects (73 females, 55 males) selected by systematic sampling. Concerning each subject age, gender, birthplace, occupation, duration of residence and building materials used in their houses were recorded. Vectors were captured both in domestic and peridomestic environments. RESULTS: Seropositive, 12.5% (16/128): females, 15.1% (11/73); males, 9.1% (5/55). Average time of residence: 6.1 years for the whole population sample and 7.4 years for the seropositive subjects. Most houses had adobe walls (76. 7%, n= 30), galvanized iron rooves (86.7%) and earthen floors (53. 4%) 80% of the walls had crevices. One hundred forty seven specimens of Triatoma infestans were captured, of which 104 (70.7%) were domestic, and 1 peridomestic Triatoma sordida. Precipitin host identification: birds, 67.5%; humans, 27.8%; rodents, 11.9%; dogs, 8. 7%; cats, 1.6%. House infestation and density indices were 53.3 and 493.0 respectively. We found 21 (14.3%) specimens of T. infestans infected with trypanosomes, 18 (85.7%) of which in domestic environments. DISCUSSION: The elements for the vector transmission of Chagas disease are present in Avaroa/Primer de Mayo and the ancient custom of keeping guinea pigs indoors adds to the risk of human infection. In neighboring Cochabamba, due to substandard quality control, contaminated blood transfusions are not infrequent, which further aggravates the spread of Chagas disease. Prompt action to check the transmission of this infection, involving additionally the congenital and transfusional modes of acquisition, is required.

[Detection of Aedes aegypti and Aedes albopictus, in an urban zone of the municipality of Catanduva, SP, after control of a Dengue epidemic]. / Detecção de Aedes aegypti e Aedes albopictus, na zona urbana do município de Catanduva-SP, após controle de epidemia de Dengue.

After the realization of control research that had in view the transmission of dengue virus, we started to monitor two kinds of entomological vigilance, Breteau Index and ovitrap. We intended to evaluate the necessary time elapsed before Aedes sp mosquitoes were again detected at the urban area of Catanduva s town (SP). The ovitraps showed positiveness for the Aedes aegypti two months after the control research, while the Breteau Index became positive only at the fourth month after the end of the referred research.

A ocorrencia de riquetsioses do grupo Rickettsia rickettsii. / The occurrence of ruckettsiosis of the group Rickettsia rickettsii

Foi realizada revisao da literatura com objetivo de atualizar as informacoes sobre a ocorrencia de riquetsioses do grupo Rickettsia rickettsii. Verificou-se que nos EUA e Europa, a incidencia da febre maculosa, vem aumentando desde 1970 ate hoje. No Brasil, foi relatado um caso presuntivo, no estado da Bahia, em 1979. Com relacao a prevencao, controle e tratamento dessa doenca e salientada a importancia de informacoes relacionadas com individuos expostos a picadas de carrapatos, notificacao de novos casos, fatores ecologicos, tecnicas laboratoriais mais especificas para a identificacao do agente etiologico, e a antibioticoterapia mais eficiente. A vacinacao e ainda referida como meio mais favoravel na prevencao da doenca, devendo ser administrada aos individuos de alto risco. No Brasil, faltam informacoes precisas sobre a ocorrencia de R. rickettsii