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Mol Biol Rep ; 50(7): 6241-6250, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37231215

ABSTRACT

Cell death is a natural mechanism for biological clearance for the maintenance of homeostasis in a dynamic microenvironment of the central nervous system. Stress and various factors can lead to imbalance between cellular genesis and cell death leading to dysfunctionality and a number of neuropathological disorders. Drug repurposing can help bypass development time and cost. A complete understanding of drug actions and neuroinflammatory pathways can lead to effective control of neurodegenerative disorders. This review covers recent advances in various neuroinflammatory pathways understanding, biomarkers, and drug repurposing for neuroprotection.


Subject(s)
Neurodegenerative Diseases , Neuroprotection , Humans , Neuroinflammatory Diseases , Drug Repositioning , Central Nervous System/metabolism , Neurodegenerative Diseases/drug therapy , Neurodegenerative Diseases/metabolism
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