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1.
Regul Toxicol Pharmacol ; 22(1): 95-100, 1995 Aug.
Article in English | MEDLINE | ID: mdl-7494907

ABSTRACT

Copper is an essential micronutrient and a potential toxic metal. The USEPA current maximum contaminant level goal (MCLG, a nonenforceable aspirational health goal) and the required treatment technique action level, both set at 1.3 mg/liter of copper are not adequately protective for infants and children under 10 years of age. Infants and children up to 10 years of age have increased susceptibility to copper toxicity. The two main reasons for the high sensitivity in this population subgroup are the presence of a normally high concentration of copper in the liver during early life and the lack of a fully developed homeostatic mechanism of copper in children under 10 years of age. This sensitive group of infants and children represents approximately 17% of the total U.S. population. The adverse health effects caused by drinking water contaminated with copper are abdominal pain, nausea, vomiting, diarrhea, headache, and dizziness. The proposed drinking water guideline of 0.3 mg/liter for copper was derived by the application of the risk assessment procedures approved by the USEPA. Drinking water containing 0.3 mg/liter of copper will provide approximately 26% of the nutritional requirement of copper. This proposed drinking water guideline (0.3 mg/liter) for copper will adequately protect health of infants, children, and adults.


Subject(s)
Copper/adverse effects , Water Pollutants/adverse effects , Water Supply/legislation & jurisprudence , Adolescent , Adult , Child , Child, Preschool , Health Policy , Humans , Infant , Infant, Newborn , No-Observed-Adverse-Effect Level , Risk , United States , United States Environmental Protection Agency , Water Supply/standards
2.
Pers J ; 60(10): 784-7, 1981 Oct.
Article in English | MEDLINE | ID: mdl-10252881
6.
Br Med J ; 4(5937): 165, 1974 Oct 19.
Article in English | MEDLINE | ID: mdl-4420126
7.
Lancet ; 1(7853): 358, 1974 Mar 02.
Article in English | MEDLINE | ID: mdl-4131205
8.
Lancet ; 1(7847): 97, 1974 Jan 19.
Article in English | MEDLINE | ID: mdl-4129241
9.
Br Med J ; 1(5851): 485, 1973 Feb 24.
Article in English | MEDLINE | ID: mdl-4689850
12.
Lancet ; 2(7668): 373, 1970 Aug 15.
Article in English | MEDLINE | ID: mdl-4194480
14.
Spec Educ ; 58(2): 6-8, 1969 Jun.
Article in English | MEDLINE | ID: mdl-4241937
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