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Turk Kardiyol Dern Ars ; 44(8): 647-655, 2016 Dec.
Article in English | MEDLINE | ID: mdl-28045410

ABSTRACT

OBJECTIVE: Treatment of chronic total occlusion (CTO) with everolimus-eluting bioresorbable vascular scaffold (BVS) is safe and effective at short-term follow-up (FU). The current study investigated clinical and angiographic outcomes after treatment of CTO with BVS at >1 year. METHODS: Thirty patients who underwent successful recanalization of 35 CTOs were included in this study. Quantitative coronary angiography (QCA) was performed at median FU period of 402 days. Clinical endpoints analyzed included all-cause mortality, cardiac death, non-fatal target vessel myocardial infarction, target vessel revascularization (TVR), symptom-driven target lesion revascularization (TLR), and BVS thrombosis. RESULTS: QCA analysis revealed in-scaffold minimal luminal diameter of 2.14±0.50 mm and late lumen loss (LLL) of 0.38±0.54 mm. One cardiac death, 5 cases with TVR, and 3 cases with TLR were detected at median FU time of 542 days. No BVS thrombosis was observed. CONCLUSION: The Absorb BVS was safe and effective in the treatment of CTO with acceptable LLL at mid-term FU, comparable to drug eluting stents.


Subject(s)
Coronary Occlusion/therapy , Drug-Eluting Stents , Everolimus/administration & dosage , Immunosuppressive Agents/administration & dosage , Aged , Coronary Angiography , Coronary Occlusion/diagnostic imaging , Female , Humans , Male , Middle Aged , Tissue Scaffolds , Treatment Outcome
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