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1.
Transplant Direct ; 4(11): e395, 2018 Nov.
Article in English | MEDLINE | ID: mdl-30534588

ABSTRACT

BACKGROUND: To assess the impact of heart transplantation (HT) on the recovery of peripheral and respiratory muscle mass and strength in patients with congestive heart failure. METHODS: The study included 23 patients with an indication for HT (patients in the waiting list [WL] group). These patients were monitored for 1.5 to 3 years after HT; 8 died before 6 months of follow-up, 15 patients completed the early follow-up period of 6 months after HT (FU6m group), 4 died between 6 months and 3 years after HT, and 11 patients completed the late follow-up period 1.5 to 3 years after HT (FU1.5-3y group). Twenty-three healthy subjects were included in the control group. The study variables included inspiratory muscle strength, expressed as the maximum inspiratory pressure (MIP); expiratory muscle strength, expressed as the maximum expiratory pressure (MEP); peripheral muscle strength, expressed as bilateral handgrip strength (bHGS); and the cross-sectional area of the bilateral psoas major muscle (CSAbPm). RESULTS: The results showed a reduction in the CSAbPm (1238.9 ± 312.3 mm2), a reduction in the bHGS (27.0 ± 5.7 kg/f), a reduction in the MIP (60.2 ± 29.8 cmH2O), and a reduction in the MEP (75.2 ± 33.4 cmH2O) in patients in the WL group compared with the healthy controls. In the time series comparison, for patients in the WL, FU6m, and FU1.5-3y groups, increases were found in the CSAbPm (1305.4 vs 1458.1 vs 1431.3 mm2, respectively), bHGS (27.3 vs 30.2 vs 34.7 kg/f, respectively), MIP (59.5 vs 85.5 vs 90.9 cmH2O, respectively), and MEP (79.5 vs 93.2 vs 101.8 cmH2O, respectively) (P < 0.00). CONCLUSIONS: Sarcopenia was observed in patients in the WL group. Patients recovered peripheral and respiratory muscle mass and strength at 3 years after HT.

2.
Aust Paediatr J ; 25(6): 351-5, 1989 Dec.
Article in English | MEDLINE | ID: mdl-2619639

ABSTRACT

One hundred and seven children with faecal incontinence were evaluated and managed over a 3 year period by a multidisciplinary team. After initial clinical assessment, evaluation of defaecatory mechanisms (using a balloon model) and assessment of personal-social development and self-concept were undertaken. Management was based on initial bowel evacuation, short-term laxatives, and habit training involving systematic use of positive reinforcement; 69 children received biofeedback conditioning. Idiopathic megacolon with constipation and soiling was the most common finding (98 cases). Other diagnoses included previously undiagnosed neurogenic bowel (three cases), post-surgical and anomalies (four cases), and psychogenic encopresis (two cases). Idiopathic megacolon was characterized by decreased rectal sensation, increased threshold for external sphincter relaxation and an inability to evacuate. Faecal incontinence was associated with an undesirably low social self-concept (70% of the 40 evaluated), but was not related to a delay in development (mean general developmental quotient = 105 +/- 8, for the 35 tested). Family psychopathology warranting referral for family therapy was found in 14 children (13%). The management programme yielded a short-term (3 months) cure rate of 68% and a long-term (12 months) cure rate of 90%, with 10% having continued soiling which varied from occasional to several incidents/week. No significant improvement in self-concept was observed overall, although marked improvements were observed in some children. We conclude that disordered defaecatory dynamics are a major determinant of faecal incontinence in children. Undesirably low social self-concepts but normal developmental ability accompany this condition. Management is facilitated by a multidisciplinary approach, acknowledging the role of both behavioural and physiological components of the problem.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Biofeedback, Psychology , Fecal Incontinence/therapy , Adolescent , Child , Child, Preschool , Family Therapy , Fecal Incontinence/physiopathology , Fecal Incontinence/psychology , Female , Follow-Up Studies , Humans , Male , Rectum/physiopathology , Self Concept , Sensation
3.
Community Dent Oral Epidemiol ; 15(3): 150-1, 1987 Jun.
Article in English | MEDLINE | ID: mdl-3474099

ABSTRACT

The present report gives prevalence values for some developmental oral anomalies in 1932 schoolchildren aged 6-12 yr in Gizan region, Saudi Arabia. The developmental oral anomalies identified in this study were: torus palatinus (1.4%), fissured tongue (0.8%), geographic tongue (0.2%), and tongue tie (0.1%). None of the following developmental oral anomalies were observed: lip pits, cleft lip and/or palate, torus mandibularis, microglossia, macroglossia or median rhomboid glossitis.


Subject(s)
Mouth Abnormalities/epidemiology , Child , Exostoses/epidemiology , Female , Humans , Male , Palate , Saudi Arabia , Tongue Diseases/epidemiology
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