ABSTRACT
Ocular trauma is the most frequent cause of monocular blindness. Ocular surface injury is the commonest among ocular injuries. Corneal abrasion and foreign body are the most common corneal injuries. A 40-year-old dentist with a history of partially penetrating corneal injury due to a pencil presented with and retained graphite bodies in the cornea 37 years after injury. His refraction was +1.0 sphere with no astigmatic error. There was no evidence of any inflammatory reaction. Intrastromal corneal graphite particles can be inert and cause no inflammatory reaction or astigmatic error even decades after injury.
ABSTRACT
The authors report a new technique to treat complete cranial nerve III palsy. A 15-year-old girl underwent botulinum toxin injection into the lateral rectus muscle, nasal transposition of both the superior and inferior oblique muscles to the medial rectus insertion, and absorbable suture globe fixation to the nasal orbital periosteum. Six months postoperatively, her primary position eye deviation was within 12 prism diopters of orthotropia with limitation of ductions in all directions. [J Pediatr Ophthalmol Strabismus. 2017;54:e13-e17].
Subject(s)
Botulinum Toxins/administration & dosage , Oculomotor Muscles/surgery , Oculomotor Nerve Diseases/therapy , Suture Techniques/instrumentation , Sutures , Vision, Binocular/physiology , Adolescent , Female , Follow-Up Studies , Humans , Injections, Intramuscular , Neurotoxins/administration & dosage , Oculomotor Muscles/innervation , Oculomotor Muscles/pathology , Oculomotor Nerve Diseases/congenital , Oculomotor Nerve Diseases/diagnosisSubject(s)
Diagnostic Techniques, Ophthalmological , Eye Diseases/diagnosis , Physical Examination/methods , Physician-Patient Relations , Adolescent , Child , Child, Preschool , Color Perception Tests , Eye Diseases/therapy , Humans , Infant , Infant, Newborn , Pediatrics , Retinoscopy/methods , Visual Acuity/physiology , Visual Field Tests/methods , Visual Fields/physiologySubject(s)
Diagnostic Techniques, Ophthalmological , Eye Diseases/diagnosis , Physical Examination/methods , Adolescent , Child , Child, Preschool , Color Perception Tests , Humans , Infant , Infant, Newborn , Retinoscopy/methods , Visual Acuity/physiology , Visual Field Tests/methods , Visual Fields/physiologyABSTRACT
We report the vitreous concentration of bevacizumab after injection for the treatment of retinopathy of prematurity (ROP). A premature neonate diagnosed with type 1 ROP was treated in both eyes with 0.625 mg intravitreal bevacizumab injection at 32 weeks' postconceptual age. Eleven weeks later there was complete regression clinically, but the patient died. Vitreous samples taken at autopsy revealed a bevacizumab vitreous concentration of 41.57 ng/ml. Histopathology of the retina showed residual preretinal neovascularization. Bevacizumab elimination from the infant vitreous is similar to that of adults, and, although complete regression was clinically apparent, it was not confirmed histopathologically.
Subject(s)
Bevacizumab/analysis , Retinopathy of Prematurity , Vitreous Body/chemistry , Angiogenesis Inhibitors , Antibodies, Monoclonal, Humanized , Gestational Age , Humans , Infant , Infant, Newborn , Intravitreal Injections , Vascular Endothelial Growth Factor AABSTRACT
PURPOSE: To assess changes in macular thickness after Descemet stripping automated endothelial keratoplasty (DSAEK), using optical coherence tomography. DESIGN: Prospective interventional case series. METHODS: setting: Institutional. patients and intervention: Thirty-three eyes of 31 patients who had Fuchs dystrophy or pseudophakic bullus keratopathy (PBK) and underwent DSAEK or combined DSAEK with cataract surgery. main outcome measure: Changes in macular thickness. RESULTS: There were 7 eyes with Fuchs endothelial dystrophy and 9 eyes with pseudophakic bullous keratopathy (PBK) that underwent DSAEK, and 17 eyes with Fuchs endothelial dystrophy and cataract that underwent combined DSAEK with phacoemulsification cataract surgery. For the whole group there was a significant increase of 19.32 µm in macular thickness at 1 month after surgery (P = .025). At 3 months the increase of 10.33 µm was not statistically significant (P = .192). For the Fuchs endothelial dystrophy there was a mean increase of 11.83 µm and a mean decrease of 9 µm at 1 and 3 months, respectively. For the PBK group there was an increase of 12.37 µm and 2.428 µm at 1 month (P = .603) and at 3 months after surgery (P = .883), respectively. These changes were not significant. For the Fuchs endothelial dystrophy and cataract group there was a significant increase of 26.50 µm at 1 month (P = .012) and 23.15 µm at 3 months after surgery (P = .038). CONCLUSIONS: Macular thickness significantly increased after DSAEK combined with cataract surgery but did not change significantly when only DSAEK was performed.
Subject(s)
Descemet Stripping Endothelial Keratoplasty , Endothelium, Corneal/surgery , Fuchs' Endothelial Dystrophy/surgery , Macula Lutea/pathology , Phacoemulsification , Pseudophakia/etiology , Aged , Cataract/complications , Endothelium, Corneal/pathology , Female , Fuchs' Endothelial Dystrophy/complications , Fuchs' Endothelial Dystrophy/pathology , Humans , Male , Organ Size , Prospective Studies , Refraction, Ocular/physiology , Tomography, Optical Coherence , Visual Acuity/physiologyABSTRACT
PURPOSE: Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunction, Horner syndrome, reduced corneal sensitivity, band keratopathy, episcleritis, uveitis, neuroretinitis, and retinal vasculitis. METHODS: Descriptive case report. RESULT: We report on the development of unilateral optic atrophy followed by ipsilateral Coats disease exudation and shallow retinal detachment in the posterior pole and inferior retina. CONCLUSIONS: Optic atrophy was not previously described in association with PRS. We describe the development of unilateral optic atrophy with subsequent CD, 5 years later , in a girl with PRS.
