ABSTRACT
Advances in prenatal diagnostic techniques have enabled early detection of potentially correctable foetal anomalies. Here, we summarise recent developments in anaesthesia for foetal surgery. Types of foetal surgery include minimally invasive, open mid-gestational and ex-utero intrapartum treatment (EXIT) procedures. Foetoscopic surgery avoids hysterotomy, with risk of uterine dehiscence, preserving the possibility of subsequent vaginal delivery. Minimally invasive procedures are performed under local or regional anaesthesia; open or EXIT procedures are usually done under general anaesthesia. Requirements include maintenance of uteroplacental blood flow, and uterine relaxation to prevent placental separation and premature labour. Foetal requirements include monitoring of well-being, providing analgesia and immobility. EXIT procedures require maintenance of placental circulation till the airway is secured, requiring multidisciplinary involvement. Here, the uterine tone must return after baby delivery to prevent major maternal haemorrhage. The anaesthesiologist plays a crucial role in maintaining maternal and foetal homeostasis and optimising surgical conditions.
ABSTRACT
Rapid advances in Artificial Intelligence (AI) have led to diagnostic, therapeutic, and intervention-based applications in the field of medicine. Today, there is a deep chasm between AI-based research articles and their translation to clinical anesthesia, which needs to be addressed. Machine learning (ML), the most widely applied arm of AI in medicine, confers the ability to analyze large volumes of data, find associations, and predict outcomes with ongoing learning by the computer. It involves algorithm creation, testing and analyses with the ability to perform cognitive functions including association between variables, pattern recognition, and prediction of outcomes. AI-supported closed loops have been designed for pharmacological maintenance of anesthesia and hemodynamic management. Mechanical robots can perform dexterity and skill-based tasks such as intubation and regional blocks with precision, whereas clinical-decision support systems in crisis situations may augment the role of the clinician. The possibilities are boundless, yet widespread adoption of AI is still far from the ground reality. Patient-related "Big Data" collection, validation, transfer, and testing are under ethical scrutiny. For this narrative review, we conducted a PubMed search in 2020-21 and retrieved articles related to AI and anesthesia. After careful consideration of the content, we prepared the review to highlight the growing importance of AI in anesthesia. Awareness and understanding of the basics of AI are the first steps to be undertaken by clinicians. In this narrative review, we have discussed salient features of ongoing AI research related to anesthesia and perioperative care.
ABSTRACT
Background and Aims: During the present COVID-19 pandemic, several inventions have been employed to protect personnel involved in intubation from inhalational exposure to the virus. In this study, we compared the effect of two barrier devices, Intubation Box versus Plastic Drape, on the time taken and difficulty in intubating a pediatric manikin. Material and Methods: Nineteen experienced anesthesiologists performed six different intubations: without barrier, with intubation box, with plastic drape; with and without a bougie, using the Latin Square Design for randomizing order of intubations. The time taken for intubation (TTI) was compared using Student's t test, and nonparametric values were analyzed using Chi-square test with Yates correction. Results: Both barrier devices increased the TTI from 14.8 (3.5) s to 19.8 (6.8) s with intubation box (P = 0.068) and 19.3 (8.9) s with plastic drape (P = 0.099). Use of bougie significantly prolonged TTI to 25.8 (6.7) s without barrier (P = 0.000), 32.5 (13.3) with intubation box (P = 0.000), and 29.8 (7.3) s with plastic drape (P = 0.000). The number of attempts was not different (P = 0.411), and the visibility was slightly impaired with both barriers (P = 0.047). The ease of intubation, even without the bougie, was significantly different compared to default, with P values of 0.009 and 0.042 for intubation box and plastic drape, respectively. The highest significance was with intubation box with bougie with a P value of 0.00017. Conclusion: Both the intubation box and plastic drape increased the time taken as well as difficulty in intubation. The extra protection afforded should be balanced against risks of hypoxia in the patient.
ABSTRACT
While the Haberland syndrome was first reported in 1970, the anaesthetic management of this rare cohort of patients has not been described. With only 54 such cases reported, describing primarily the unilateral cutaneous, ocular, and neurologic malformations associated with this syndrome without focussing on the anaesthetic management. We describe the case of a 7 year old case of Harberland syndrome with special focus on the difficulties faced by us in mask ventilation, as well as intubation and the need for elective ventilation and planned extubation. We also discuss the precautions to be taken while undertaking such a case like preparations for emergency tracheostomy and possibility of re-intubation after extubation. A meticulous preoperative workup along with neurological and airway examination along with preparation for elective ventilation and tracheostomy is a prerequisite for the successful management of this case.
