[A comparative description of amyloidosis in monkeys]. / Sravnitel'naia kharakteristika amiloidoza u obez'ian.

The paper contains the results of a postmortem study of 461 cases of amyloidosis in monkeys of 4 species (Papio hamadryas, Macaca mulatto, Macaca fascicularis and Macaca nemestrina) from the Sukhumi and Adler primatological facilities. Emergence of amyloidosis was found to be dependent on age; the frequency ratio at which separate organs are affected is presented; the specific disease signs are described for different monkey species. Generalized and isolated cases of amyloidosis are elucidated with the liver being the most vulnerable organ in macaques (64%) and the kidneys--in baboons (94%). A comparative description of different forms of amyloidosis in monkey and man was made use of to suggest using the amyloidosis in monkeys as a model process for studying the pathology in man.

Amyloidosis in macaques in adler primatological center.

Results of pathomorphological studies of 133 amyloidosis cases in macaques of 3 species (M. mulatta, M. nemestrina, and M. fascicularis) in the Adler Primatological Center are presented. A relationship between the development of amyloidosis and animal age is detected and the incidence of involvement of various organs is determined. Generalized and isolated forms of amyloidosis are described, the most incident of which (36.8%) was hepatic amyloidosis. Simian and human amyloidosis are compared. Amyloidosis in macaques can be used as the model process for studies of amyloidosis in humans.

[Dispensary registration groups and follow-up periods of patients with silicotuberculosis]. / O gruppakh dispansernogo ucheta i srokakh nabliudeniia bol'nykh silikotuberkulezom.

Silicosis is the most common and most frequently tuberculosis-complicated pneumoconiosis with poor prognosis. So a procedure for following up patients with silicotuberculosis requires revision and elaboration. Long-term follow-ups have made it possible to define early signs of this disease and to propose a number of techniques for its early diagnosis, such as chest computed tomography and polarization serum crystal microscopy. Specific recommendations on follow-ups of patients with silicosis and silicotuberculosis by a phthisiologist are laid down.

[Impact of tuberculosis in penal labor facilities on the epidemiological situation in the Sverdlovsk region]. / Vliianie tuberkuleza v ispravitel'no-trudovykh uchrezhdeniiakh na épidemiologicheskuiu situatsiiu v Sverdlovskoi oblasti.

The unfavourable tuberculosis situation in the corrective labour facilities affects the main rates of tuberculosis in the region. Presently, the total registered cases of tuberculosis among prisoners are 36.7 times as high as those in the age-matched general population of the Sverdlovsk Region. The rates of relapses, incidence, death due to tuberculosis show 72.0-, 36.1-, and 10.4-fold increases, respectively. Almost every 10 persons from the labour corrective facilities suffer from active tuberculosis. In the past decade, the growth rates of main tuberculosis parameters in the corrective labour facilities were much higher (total tuberculosis morbidity by 2.1 times, relapses by 2.1 times, general morbidity by 1.7 times, and total tuberculosis mortality by 2.8 times) than those in the region's general population. Extrapulmonary tuberculosis was not virtually detected in the labour corrective facilities) due to the lack of special diagnostic methods.

[Efficiency of computed tomography in diagnosis of silicotuberculosis]. / Effektivnost' komp'iuternoi tomografii v diagnostike silikotuberkuleza

The routine methods X-ray study and computed tomography (CT) were compared in a group of patients engaged in fireproof industry. CT yields valuable additional data in early silicotuberculosis, which makes it possible to follow the extent of a silicotuberculous process more completely, to make a better diagnosis of nodal and focal shadows, to identify small decay cavities in the foci and infiltrates. CT is the method of choice in following up patients with silicotuberculosis.

[Problems in the evaluation of predisposing factors to pulmonary tuberculosis]. / K probleme otsenki predraspolozhennosti k tuberkulëzu lëgkikh.

Genetic predisposition is an important factor in pulmonary tuberculosis. The pattern of dermatoglyphic indicators is thought a reliable marker of such predisposition. Selective character of the disease emergence is related with an unfavorable combination of genetic and extra-genetic risk factors in an individual. A comprehensive assessment of the above factors may contribute to a reliable prediction of a high risk to develop tuberculosis.