ABSTRACT
The effects of the calcium blocking agent diltiazem upon esophageal motility was studied with electromanometric technique in 23 patients. In 10 achalasic patients lower esophageal sphincter pressure was reduced in 40.1%, in the remaining 13 in only 19.15%. Other parameters showed only minor changes such as reduction in the pressure of contractile waves in the body of the esophagus.
Subject(s)
Benzazepines/pharmacology , Diltiazem/pharmacology , Esophageal Diseases/physiopathology , Esophagus/physiopathology , Esophageal Achalasia/physiopathology , Esophagogastric Junction/physiopathology , Esophagus/drug effects , Female , Humans , Male , Manometry , Middle Aged , Peristalsis/drug effectsABSTRACT
Los efectos del bloqueante calcico "diltiazem" fueron estudiados mediante electromanometria esofagica en 23 pacientes.En los enfermos de acalasia se observo una reduccion de la presion del esfinter esofagico inferior del 40.1% mientras que en el resto del grupo fue del 19.15%. Los otros parametros estudiados sufrieron variaciones menores como, por ejemplo reduccion en la presion de ondas contractiles del cuerpo del esofago
Subject(s)
Humans , Male , Female , Diltiazem , Esophageal Diseases , Esophagogastric Junction , Esophagus , PressureABSTRACT
The effects of the calcium blocking agent diltiazem upon esophageal motility was studied with electromanometric technique in 23 patients. In 10 achalasic patients lower esophageal sphincter pressure was reduced in 40.1
, in the remaining 13 in only 19.15
. Other parameters showed only minor changes such as reduction in the pressure of contractile waves in the body of the esophagus.
ABSTRACT
Los efectos del bloqueante calcico "diltiazem" fueron estudiados mediante electromanometria esofagica en 23 pacientes.En los enfermos de acalasia se observo una reduccion de la presion del esfinter esofagico inferior del 40.1% mientras que en el resto del grupo fue del 19.15%. Los otros parametros estudiados sufrieron variaciones menores como, por ejemplo reduccion en la presion de ondas contractiles del cuerpo del esofago
Subject(s)
Humans , Male , Female , Diltiazem , Esophagus , Esophageal Diseases , Esophagogastric Junction , PressureABSTRACT
The esophageal response studied in the systemic illness has been developed clearly in the body of the esophagus as well as in the lower esophageal sphincter, showing important alterations in the peristalsis and a significant fall of lower esophageal sphincter pressure, proving conditions such as those in which gastro-esophageal reflux is produced. The authors studied the esophageal motility in 10 patients with progressive systemic sclerosis by electromanometry by means of an open-tipped catheters system. They found that the pressure of the inferior esophageal sphincter was altered in the 100 per cent of the cases; in 50% of the patients there was a lack of peristaltic waves and in the remaining 50% the middle pressure was less than in normal subjects. It was observed dysquinethic waves in 40% of the cases. The intensity of the epidermic compromise is no related with alterations in the esophageal functioning.
Subject(s)
Esophagus/physiopathology , Scleroderma, Systemic/physiopathology , Esophagogastric Junction/physiopathology , Gastrointestinal Motility , Humans , ManometryABSTRACT
La repercusion esofagica de la enfermedad sistemica estudiada se manifesto muy claramente, tanto en el cuerpo del organo como en el esfinter inferior, caracterizando importantes alteraciones en la peristalsis y una significativa reduccion en la presion del esfinter inferior, determinante de condiciones tales como aquellas en las que se produce reflujo gastro-esofagico
Subject(s)
Esophagus , Gastrointestinal Motility , Manometry , Scleroderma, SystemicABSTRACT
Se realizo un estudio prospectivo randomizado en 118 pacientes para probar la utilidad de la antibioticoterapia profilactica de la infeccion quirurgica en operaciones "limpias". Se utilizo un esquema original con monodosis preoperatoria inmediata de gentamicina y cefalotina. Se demuestra estadisticamente la reduccion en las complicaciones septicas de la herida operatoria en el grupo tratado. No se observaron otro tipo de complicaciones que las de la herida. En ningun caso estas fueron severas
Subject(s)
Humans , Cephalothin , Gentamicins , Surgical Wound Infection , Postoperative Complications , Preoperative CareSubject(s)
Humans , Pancreatitis , Abscess , Fistula , Gastrointestinal Hemorrhage , Mortality , ShockABSTRACT
The esophageal response studied in the systemic illness has been developed clearly in the body of the esophagus as well as in the lower esophageal sphincter, showing important alterations in the peristalsis and a significant fall of lower esophageal sphincter pressure, proving conditions such as those in which gastro-esophageal reflux is produced. The authors studied the esophageal motility in 10 patients with progressive systemic sclerosis by electromanometry by means of an open-tipped catheters system. They found that the pressure of the inferior esophageal sphincter was altered in the 100 per cent of the cases; in 50
of the patients there was a lack of peristaltic waves and in the remaining 50
the middle pressure was less than in normal subjects. It was observed dysquinethic waves in 40
of the cases. The intensity of the epidermic compromise is no related with alterations in the esophageal functioning.
ABSTRACT
La repercusion esofagica de la enfermedad sistemica estudiada se manifesto muy claramente, tanto en el cuerpo del organo como en el esfinter inferior, caracterizando importantes alteraciones en la peristalsis y una significativa reduccion en la presion del esfinter inferior, determinante de condiciones tales como aquellas en las que se produce reflujo gastro-esofagico
Subject(s)
Scleroderma, Systemic , Esophagus , Manometry , Gastrointestinal MotilityABSTRACT
Se realizo un estudio prospectivo randomizado en 118 pacientes para probar la utilidad de la antibioticoterapia profilactica de la infeccion quirurgica en operaciones "limpias". Se utilizo un esquema original con monodosis preoperatoria inmediata de gentamicina y cefalotina. Se demuestra estadisticamente la reduccion en las complicaciones septicas de la herida operatoria en el grupo tratado. No se observaron otro tipo de complicaciones que las de la herida. En ningun caso estas fueron severas
