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J Atheroscler Thromb ; 25(5): 405-409, 2018 May 01.
Article in English | MEDLINE | ID: mdl-29118310

ABSTRACT

AIMS: The present study aimed to determine the epidemiological aspects of medico-legal autopsies and manifestation of coronary atherosclerosis. METHODS: This was a cross sectional study involving 222 cases recruited from National Institute of Forensic Medicine (NIFM) Hospital Kuala Lumpur (HKL) and Department of Forensic Medicine Hospital Sungai Buloh (HSgB) for a period of 15 months, from December 2012 to April 2014. Sociodemographic and autopsy findings, including the cause and manner of death were documented. RESULTS: Male and female subjects aged 18-70 years were recruited. Males contributed to 86% of the total subjects and comprised 61% of young adults. Road traffic accidents were the primary cause of death, contributing almost 50% of the subjects. One third of the cases comprised of death due to natural causes, wherein almost 75% of the subjects within this category succumbed to sudden cardiac death. Coronary artery disease (CAD) contributed to 60% of the sudden cardiac death (SCD). Single and double-vessel diseases were the most common pattern of atherosclerosis. In almost 80% of CAD cases, atherosclerosis affected the left anterior descending artery (LAD). CONCLUSION: Cardiovascular diseases were the most significant natural cause of sudden death with a staggering figure of 75%. CAD was the single most commonly encountered pathology within the SCD. Most cases presented with single and double-vessel diseases, observed in all subjects, as well as the young adult population.


Subject(s)
Coronary Artery Disease/complications , Coronary Artery Disease/mortality , Death, Sudden, Cardiac/etiology , Adolescent , Adult , Aged , Autopsy , Cause of Death , Cross-Sectional Studies , Death, Sudden, Cardiac/epidemiology , Female , Follow-Up Studies , Humans , Malaysia/epidemiology , Male , Middle Aged , Prognosis , Survival Rate , Young Adult
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