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Control and Elimination of Extensively Drug-Resistant Acinetobacter baumanii in an Intensive Care Unit.
Chamieh, Amanda; Nawfal, Tania Dagher; Ballouz, Tala; Afif, Claude; Juvelekian, George; Hlais, Sani; Rolain, Jean-Marc; Azar, Eid.
Emerg Infect Dis ; 25(10): 1928-1931, 2019 10.
Article in English | MEDLINE | ID: mdl-31538925

ABSTRACT

We decreased antimicrobial drug consumption in an intensive care unit in Lebanon by changing to colistin monotherapy for extensively drug-resistant Acinetobacter baumanii infections. We saw a 78% decrease of A. baumanii in sputum and near-elimination of blaoxa-23-carrying sequence type 2 clone over the 1-year study. Non-A. baumanii multidrug-resistant infections remained stable.


Subject(s)
Acinetobacter Infections/prevention & control , Acinetobacter baumannii/drug effects , Cross Infection/prevention & control , Intensive Care Units , Acinetobacter Infections/drug therapy , Aged , Anti-Bacterial Agents/therapeutic use , Antimicrobial Stewardship/methods , Cross Infection/drug therapy , Disease Eradication/methods , Drug Resistance, Multiple, Bacterial , Female , Humans , Lebanon/epidemiology , Male , Sputum/microbiology
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