Effect of Adenotonsillectomy on Spectral and Acoustic Characteristics.

Acoustic analysis and perceptual analysis has been extensively used to assess the speech and voice among individual with voice disorders. These methods provide objective, quantitative and precise information on the speech and voice characteristics in any given disorder and help in monitoring any recovery, deterioration, or improvement in an individual's speech and also differentiate between normal and abnormal speech and voice characteristics. The present study was carried out to investigate the spectral characteristics (formant frequency parameters and formant centralization ratios) and voice characteristics (Acoustic parameters of voice) changes in individuals following adenotonsillectomy. A total of 34 participants participated in the study with a history of adenotonsillar hypertrophy. Spectral and acoustic voice parameters were analyzed across the three-time domains, before surgery (T0), 30 days (T1), and 90 days (T2) after surgery. Data was analyzed statistically using the SPSS software version-28.0.0.0. Descriptive statistics were used to find the mean and standard deviation. Repeated measures of ANOVA were used to compare the pre and post-experimental measures for spectral and acoustic, voice parameters. The derived parameter of acoustic vowel space (formant centralization ratio 3) was compared across three conditions timelines. The results revealed that acoustic vowel space measure and formant frequency measures were significantly increased in pre and post-operative conditions across the three timelines. A significant difference was obtained across the acoustic parameters across the time domains. Adenotonsillectomy has been proved to be an efficient surgical procedure in treating children with chronic adenotonsillitis. The results obtained have indicated an overall improvement in the spectral and acoustic voice parameters thereby highlighting the need for adenotonsillectomy at the right time and at the right age.

Videofluoroscopy Practice in India: A Survey of Speech-Language Pathologists.

Owing to differences in clinical approaches toward videofluoroscopic swallowing studies (VFSS), professional and governing bodies in some countries have implemented guidelines for performing VFSS. However, in India, the establishment of such practice guidelines is in initial stages of acceptance and there are no uniform guidelines. The aim of the current study was to investigate and describe the clinical practice patterns related to VFSS assessments among Speech-Language Pathologists (SLPs) in India. An electronic survey consisting of 34 questions categorized into four main sections (demographic details and education; current practice; instrumental and technical considerations; protocol and assessment methods) was sent to SLPs registered with the Indian Speech and Hearing Association (ISHA) through email and social media from August 2020 to January 2021. A total of 129 eligible responses were received. More than 50% of the participants used a standard assessment and analysis protocol. Barium and water-soluble contrasts were mostly used, and 97% of participants did not know what percent weight to volume (w/v) or volume to volume (v/v) contrast to fluid were used. Considerable amount of variability was observed in the responses of our participants, which was consistent with international surveys of VFSS practice patterns. Lack of adequate radiation safety measures was also observed. Our findings suggest a need to increase awareness and training among Indian SLPs in technical and procedural aspects of VFSS, and more sensitization toward radiation safety. ISHA should consider forming a committee to develop and adopt uniform nationwide practices in VFSS. Future studies exclusively investigating barriers and facilitators to VFSS practice in the Indian scenario are necessary.

Can Straw Phonation Be Considered As Vocal Warm Up Among Speech Language Pathologists?

OBJECTIVE: Straw phonation exercises have been proved to be effective in improving voice quality among persons with voice pathology. The aim of the study was to investigate the effects of straw phonation as a warm-up exercise on maximum phonation duration, acoustic, and perceptual parameters of voice among Speech Language Pathologists. STUDY DESIGN: The study adopted a pretest-posttest design. MATERIALS AND METHOD: Twenty-five females with the mean age range of 20.87 ± 1.15 years participated in the study and completed a series of straw phonation exercises for three cycles. Maximum phonation duration, acoustic, and self-perceptual measures were assessed before and after the straw phonation exercises. F0, jitter, shimmer, nose to harmonic ratio, intensity, F1, F2, F3, F4, Maximum phonation duration, and the post self-perceptual measures were analyzed. RESULTS: The results indicated a significant improvement in the F0, intensity, F1, F2, F4, Maximum phonation duration, and self-perceptual measures. CONCLUSION: Straw phonation exercises provides an easy and effective warm up technique to improve the voice quality among Speech Language Pathologists and can be considered before conducting therapy sessions.

Adaptation and Validation of Reflux Symptom Index Into Kannada Language.

OBJECTIVE: The present study aimed to translate, validate the Reflux Symptom Index in Kannada language and to compare its outcomes between normal individuals and individuals with laryngopharyngeal reflux. STUDY DESIGN: Cross sectional study design MATERIALS AND METHOD: : The English version of Reflux Symptom Index was translated into Kannada language using standard procedures. A total of 162 participants participated in the study, 81 with laryngopharyngeal reflux and 81 controls. Internal consistency, test-retest reliability, and clinical validity were calculated. RESULTS: Results revealed that the Kannada Reflux Symptom Index exhibited an excellent internal consistency (α = 0.87). The average intra-class correlation coefficient was 0.90 and 0.92, indicating excellent test-retest reliability. Independent sample t test revealed a statistically significant difference between the total scores of both the groups, thereby exhibiting good clinical validity of RSI-K (t = 42.71, df = 158, P < 0.001). CONCLUSION: The Kannada Reflux Symptom Index is a reliable and valid tool for use in patients with laryngopharyngeal reflux. It can be used as a quick tool to assess laryngopharyngeal reflux.

Influence of Eu3+ on the Structure and Photophysical Properties in (Y,Gd)F3 Nanophosphors.

The scientific community has shown a growing interest in relating to the lanthanide based luminescent materials and it has made an effort to develop them. Among these several luminescent materials, we have proposed to developed (Y,Gd)F3 nanophosphors doped with distinct of Eu3+ concentrations using modified hydrothermal process. The effect of co-doping of rare earth activators to the host lattice structure and morphology are investigated using different analytical techniques. The diffuse reflectance spectra reveal a tuning of optical band gap due to substitutions. From the extensive XPS analysis, Gd and Eu are found to be in a stable ionic state of +3 which is replacing Y3+ in YF3 host. Photoluminescence emission spectra of the nanophosphors are excited by near ultraviolet (UV, 393 nm) excitation. From photoluminescence study, the intensity variation is observed for emission peak at 591 nm and fluorescence quenching occurs at higher doping level. This effect subsequently explained on the frame work of local symmetry and nonradiative transfer among multipole-multipole interaction. At 393 nm excitation Eu3+ (2, 3, 5, 7, 10 at %) doped (Y, Gd) F3 show CIE chromaticity coordinates shifted to red regions with increase in Eu doping levels. Because of the longer decay time these phosphors can be used for bio-labeling and other similar applications.

Tunable luminescence of Eu3+ -activated CaWO4 nanophosphors via Bi3+ incorporation.

A series of CaWO4 :3Eu3+ :xBi3+ (x = 2, 5, 7 and 10 at.%) nanophosphors was prepared through the efficient low-temperature ethylene glycol route. Their structural, as well as photophysical, properties were studied. X-ray diffraction analysis and a X-ray photoelectron spectroscopy survey confirmed that the Bi3+ and Eu3+ ions incorporated perfectly into Ca2+ and without disturbing the lattice. The samples exhibited almost spherical morphology with average particle sizes from 10 to 30 nm. For the nanoparticles, Fourier transform infrared spectroscopy featured broad absorption bands around 871 and 778 cm-1 that were due to antisymmetric stretching, whereas a peak at 435 cm-1 was assigned to antisymmetric bending vibrations of the bonds in [WO4 2- ] clusters. The nanophosphors showed orange-red luminescence, which was further tuned to red by incorporation of sensitizer Bi3+ ions. This colour tuning of the nanoparticles is described in the context of energy transfer from the WO4 2- group to sensitizer Bi3+ and activator Eu3+ ions under 394 nm excitation. A CIE diagram supports this colour tunability.

Effect of Bhramari Pranayama on the Acoustic and Aerodynamic Parameters of Voice in Normophonic Females.

SUMMARY OBJECTIVE: Pranayama is known for improving various health conditions. The present study is aimed at investigating the effects of bhramari pranayama on aerodynamic and acoustic parameters of voice in healthy individuals. STUDY DESIGN: This is a pretest-posttest design study. METHODS: A total of 24 participants in the age range of 20 to 25 years completed the bhramari pranayama regimen for 30 sessions. Aerodynamic and acoustic assessments were done before and after pranayama sessions. Maximum phonation duration, pitch, loudness, subglottal pressure, glottal airflow, laryngeal resistance and conductance along with acoustical parameters such as average F0, jitter, and shimmer, soft phonation index, noise to harmonic ratio, cepstral peak prominence, and smoothened cepstral peak prominence were analysed. RESULTS: The results revealed significant improvement in the maximum phonation duration, glottal airflow and pressure, average fundamental frequency, and cepstral peak prominence after practice suggesting that it has an effect on voice parameters. CONCLUSION: Bhramari pranayama is effective in improving the acoustic and aerodynamic parameters of voice. The same needs to be investigated in hyper- and hypofunctional voice disorders in the future studies.

Hazards and Health Risks Encountered by Manual Sand Dredgers from Udupi, India: A Cross-sectional Study.

INTRODUCTION: Globalization and urbanization have resulted in an increased demand on sand dredging. Legal and environmental restrictions on automated dredging have led to a rise in manual technique. The working techniques and environment involved in manual sand dredging may expose the workers to multiple work related disorders. AIM: To determine the health risks and occupational hazards involved in manual sand dredging. MATERIALS AND METHODS: An assessment schedule was developed and content was validated by five experts for the study. A cross-sectional study was then conducted using this assessment schedule. Thirty manual sand dredgers were recruited from three randomly selected docks on Swarna riverbed in Udupi district, Karnataka, India. A detailed work and worksite assessments were conducted using systematic observation and close-ended questions. Work-related health risk evaluation included onsite-evaluation and self-reported health complains. RESULTS: The prevalence of musculoskeletal pain and discomfort was 93.34% with lower back (70%), shoulder (56.7%) and neck (46.7%) involvements being most common regions. Prevalence of sensory deficits at multiple site and ear pain was 66.6% and 76.6% respectively. All the workers recruited, complained of dermatological and ophthalmic involvements. Also, lack of health and safety measures like personal protective devices and security schemes were identified. CONCLUSION: This study shows a high prevalence of multiple work-related disorders and hazards involved in manual sand dredging, a highly demanding job in coastal Karnataka. Lack of health and safety measures were also identified.

Simultaneous pretreatment and sacchariffication of rice husk by Phanerochete chrysosporium for improved production of reducing sugars.

Phanerochete chrysosporium, the white-rot fungus, (a best source for lignolytic enzymes system) was used in the biological pretreatment of rice husk for reducing sugars production. Usually reducing sugar production through biochemical process involves two steps: solid state fermentation (SSF) of fungal pretreatment for delignification, subsequently pretreated biomass subjected to enzymatic hydrolysis. During the fungal pretreatment of rice husk for reducing sugar production along with cellulase and xylanse, the activities of lignin degradation-related enzymes such as lignin peroxidases (LiP), GLOX (glyoxidase), and aryl alcohol oxidases (AAO), were observed. The fungal pretreated rice husk produced highest (895.9 mg/ml/2g of rise husk) reducing sugars on 18th day of fungal treatment. This method may be good alternative to avoid operational costs associated with washing and the removal of inhibitors during the conventional pretreatment methods.

Preparation and in vitro in vivo evaluation of aceclofenac loaded alginate microspheres: an investigation of effects of polymer using multiple comparison analysis.

The aim of this present research work was to prepare and evaluate alginate microspheres of aceclofenac by ionic gelation method for targeting the drug release in intestinal region and decrease distinct tissue protection in the stomach. This method offers to prepare microspheres which are important in controlling the release rate and the absorption of aceclofenac from the intestinal region. Variation in polymer concentration was studied systemically for their influence on the encapsulation efficacy, particle size and in vitro drug release. The enteric nature of the microspheres showed very less amount of drug released in acidic medium. The mucoadhesion property was strongly dependent on the pH of the medium and the polymer concentration in the formulations. In vitro drug release study proposed a mixed drug release mechanism, partially involving the sphere matrix disintegration and drug diffusion of the microspheres. Holm-Sidak multiple comparison analysis suggested a significant difference in measured t50% values among all the microsphere formulations. In vivo studies revealed that the anti-inflammatory effect induced by the aceclofenac loaded alginate microspheres was significantly high and prolonged than that induced by the pure aceclofenac. So, this aceclofenac loaded alginate microspheres exhibited promising properties to improve the patient compliance by controlling and prolonging the systemic absorption of aceclofenac along with a distinct tissue protection in the stomach.